Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate.
about
Kirsten Ras* oncogene: Significance of its discovery in human cancer researchIdentification of Binding Targets of a Pyrrole-Imidazole Polyamide KR12 in the LS180 Colorectal Cancer GenomeIonic Liquid Solvation versus Catalysis: Computational Insight from a Multisubstituted Imidazole Synthesis in [Et2NH2][HSO4].Synthetic genome readers target clustered binding sites across diverse chromatin states.DNA Interstrand Crosslinks by H-pin Polyamide (S)-seco-CBI Conjugates.Targeting RAS signaling pathway as a potential therapeutic target in the treatment of colorectal cancer.Comparative Analysis of DNA-Binding Selectivity of Hairpin and Cyclic Pyrrole-Imidazole Polyamides Based on Next-Generation Sequencing.Genetic regulation of the RUNX transcription factor family has antitumor effectsDeciphering the genomic targets of alkylating polyamide conjugates using high-throughput sequencing.Structural basis of DNA duplex distortion induced by thiazole-containing hairpin polyamides.A polyamide inhibits replication of vesicular stomatitis virus by targeting RNA in the nucleocapsid.Impairment of K-Ras signaling networks and increased efficacy of epidermal growth factor receptor inhibitors by a novel synthetic miR-143.Targeting KRAS in metastatic colorectal cancer: current strategies and emerging opportunities.COL1A1: A potential therapeutic target for colorectal cancer expressing wild-type or mutant KRASSuppression of GPR56 expression by pyrrole-imidazole polyamide represents a novel therapeutic drug for AML with high EVI1 expressionSelective targeting of KRAS oncogenic alleles by CRISPR/Cas9 inhibits proliferation of cancer cells
P2860
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P2860
Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
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2015年學術文章
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name
Inhibition of KRAS codon 12 mu ...... imidazole polyamide conjugate.
@en
Inhibition of KRAS codon 12 mu ...... imidazole polyamide conjugate.
@nl
type
label
Inhibition of KRAS codon 12 mu ...... imidazole polyamide conjugate.
@en
Inhibition of KRAS codon 12 mu ...... imidazole polyamide conjugate.
@nl
prefLabel
Inhibition of KRAS codon 12 mu ...... imidazole polyamide conjugate.
@en
Inhibition of KRAS codon 12 mu ...... imidazole polyamide conjugate.
@nl
P2093
P2860
P356
P6366
P1476
Inhibition of KRAS codon 12 mu ...... imidazole polyamide conjugate.
@en
P2093
Allan Balmain
Atsushi Takatori
Hirokazu Sugimoto
Hiroki Nagase
Hiroshi Sugiyama
Ken-ichi Shinohara
Kiriko Hiraoka
Kyoko Fujiwara
Nobuko Koshikawa
Rhys Dylan Taylor
P2860
P2888
P356
10.1038/NCOMMS7706
P407
P577
2015-04-27T00:00:00Z
P6179
1013991715
P6366
2062852255