Somatic cells with a heavy mitochondrial DNA mutational load render induced pluripotent stem cells with distinct differentiation defects.
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Aged iPSCs display an uncommon mitochondrial appearance and fail to undergo in vitro neurogenesis.Concise review: hematopoietic stem cell aging and the prospects for rejuvenationPluripotent stem cell energy metabolism: an updateHuman iPS Cell-Derived Germ Cells: Current Status and Clinical PotentialAccumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and Reduces Survival.Study of mitochondrial respiratory defects on reprogramming to human induced pluripotent stem cells.Concise Review: Induced Pluripotent Stem Cell-Based Drug Discovery for Mitochondrial Disease.TALEN-mediated shift of mitochondrial DNA heteroplasmy in MELAS-iPSCs with m.13513G>A mutation.The functional genomics laboratory: functional validation of genetic variants.Mitochondria and the dynamic control of stem cell homeostasis.Mitochondrial Function and Dynamics Imaged In Vivo
P2860
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P2860
Somatic cells with a heavy mitochondrial DNA mutational load render induced pluripotent stem cells with distinct differentiation defects.
description
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Somatic cells with a heavy mit ...... tinct differentiation defects.
@en
Somatic cells with a heavy mit ...... tinct differentiation defects.
@nl
type
label
Somatic cells with a heavy mit ...... tinct differentiation defects.
@en
Somatic cells with a heavy mit ...... tinct differentiation defects.
@nl
prefLabel
Somatic cells with a heavy mit ...... tinct differentiation defects.
@en
Somatic cells with a heavy mit ...... tinct differentiation defects.
@nl
P2093
P2860
P356
P1433
P1476
Somatic cells with a heavy mit ...... tinct differentiation defects.
@en
P2093
Gudmundur L Norddahl
Martin Wahlestedt
Niels-Bjarne Woods
Roksana Moraghebi
P2860
P304
P356
10.1002/STEM.1630
P577
2014-05-01T00:00:00Z