Perforin-mediated effector function within the central nervous system requires IFN-gamma-mediated MHC up-regulation.
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Gamma Interferon Plays a Crucial Early Antiviral Role in Protection against West Nile Virus InfectionMurine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/MicrogliaMicroRNA-155 enhances T cell trafficking and antiviral effector function in a model of coronavirus-induced neurologic diseaseInduction of class I antigen processing components in oligodendroglia and microglia during viral encephalomyelitis.RNase L mediated protection from virus induced demyelination.Gamma interferon signaling in oligodendrocytes is critical for protection from neurotropic coronavirus infectionVirus-specific and bystander CD8 T cells recruited during virus-induced encephalomyelitisExpression of matrix metalloproteinases and their tissue inhibitor during viral encephalitis.The pathogenesis of murine coronavirus infection of the central nervous system.Protection against polyoma virus-induced tumors is perforin-independentPromoting remyelination: utilizing a viral model of demyelination to assess cell-based therapiesMice deficient in interferon-gamma or interferon-gamma receptor 1 have distinct inflammatory responses to acute viral encephalomyelitis.Expression of the mouse hepatitis virus receptor by central nervous system microgliaMemory T cells persisting in the brain following MCMV infection induce long-term microglial activation via interferon-γ.Effects of an epitope-specific CD8+ T-cell response on murine coronavirus central nervous system disease: protection from virus replication and antigen spread and selection of epitope escape mutants.Synergistic roles of antibody and interferon in noncytolytic clearance of Sindbis virus from different regions of the central nervous system.Myd88 Initiates Early Innate Immune Responses and Promotes CD4 T Cells during Coronavirus Encephalomyelitis.IFN-γ protects from lethal IL-17 mediated viral encephalomyelitis independent of neutrophils.Coronavirus infection of the central nervous system: host-virus stand-off.Type I interferons are essential in controlling neurotropic coronavirus infection irrespective of functional CD8 T cells.The chemokine receptor CXCR2 and coronavirus-induced neurologic disease.CD4 T cells contribute to virus control and pathology following central nervous system infection with neurotropic mouse hepatitis virus.NKG2D receptor signaling enhances cytolytic activity by virus-specific CD8+ T cells: evidence for a protective role in virus-induced encephalitis.Evidence for differential roles for NKG2D receptor signaling in innate host defense against coronavirus-induced neurological and liver disease.Astrocyte-derived CXCL10 drives accumulation of antibody-secreting cells in the central nervous system during viral encephalomyelitis.Priming of CD8+ T cells during central nervous system infection with a murine coronavirus is strain dependent.Generation of a protective T-cell response following coronavirus infection of the central nervous system is not dependent on IL-12/23 signaling.Perforin and gamma interferon-mediated control of coronavirus central nervous system infection by CD8 T cells in the absence of CD4 T cellsMemory CD4+ T-cell-mediated protection from lethal coronavirus encephalomyelitis.Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infectionInterleukin-12 (IL-12), but not IL-23, deficiency ameliorates viral encephalitis without affecting viral control.Mouse hepatitis virus infection of the CNS: a model for defense, disease, and repair.IFN-gamma-mediated suppression of coronavirus replication in glial-committed progenitor cells.The Biology of Persistent Infection: Inflammation and Demyelination following Murine Coronavirus Infection of the Central Nervous SystemIfit2 deficiency results in uncontrolled neurotropic coronavirus replication and enhanced encephalitis via impaired alpha/beta interferon induction in macrophages.Murine coronavirus neuropathogenesis: determinants of virulence.Immune responses to non-tumor antigens in the central nervous system.Role of the inflammasome-related cytokines Il-1 and Il-18 during infection with murine coronavirus.Distinct CD4 T-cell effects on primary versus recall CD8 T-cell responses during viral encephalomyelitis.Protective Humoral Immunity in the CNS Requires Peripheral CD19-Dependent Germinal Center Formation Following Coronavirus Encephalomyelitis.
P2860
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P2860
Perforin-mediated effector function within the central nervous system requires IFN-gamma-mediated MHC up-regulation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Perforin-mediated effector fun ...... ma-mediated MHC up-regulation.
@en
Perforin-mediated effector fun ...... ma-mediated MHC up-regulation.
@nl
type
label
Perforin-mediated effector fun ...... ma-mediated MHC up-regulation.
@en
Perforin-mediated effector fun ...... ma-mediated MHC up-regulation.
@nl
prefLabel
Perforin-mediated effector fun ...... ma-mediated MHC up-regulation.
@en
Perforin-mediated effector fun ...... ma-mediated MHC up-regulation.
@nl
P2093
P1476
Perforin-mediated effector fun ...... ma-mediated MHC up-regulation.
@en
P2093
Beatriz Parra
Cornelia C Bergmann
David R Hinton
Maureen Morrison
Ramakrishna Chandran
Stephen A Stohlman
P304
P356
10.4049/JIMMUNOL.170.6.3204
P407
P577
2003-03-01T00:00:00Z