Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.
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Counteracting Protein Kinase Activity in the Heart: The Multiple Roles of Protein PhosphatasesProfiling Subcellular Protein Phosphatase Responses to Coxsackievirus B3 Infection of Cardiomyocytes.Dual-Specificity Phosphatase 4 Overexpression in Cells Prevents Hypoxia/Reoxygenation-Induced Apoptosis via the Upregulation of eNOSRedox activation of DUSP4 by N-acetylcysteine protects endothelial cells from Cd²⁺-induced apoptosis.Genome-wide DNA methylation profiles and their relationships with mRNA and the microRNA transcriptome in bovine muscle tissue (Bos taurine).Activation of the retinoid X receptor modulates angiotensin II-induced smooth muscle gene expression and inflammation in vascular smooth muscle cellsMyocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38α MAPK during insulin resistance.The dual-specificity phosphatase 2 (DUSP2) does not regulate obesity-associated inflammation or insulin resistance in mice.p38α regulates SERCA2a function.Dual-Specificity Phosphatase 4 Regulates STAT5 Protein Stability and Helper T Cell Polarization.Imbalanced signal transduction in regulatory T cells expressing the transcription factor FoxP3.Modulation of p38 kinase by DUSP4 is important in regulating cardiovascular function under oxidative stressSignal-dependent repression of DUSP5 by class I HDACs controls nuclear ERK activity and cardiomyocyte hypertrophy.Cardiomyocyte GTP Cyclohydrolase 1 Protects the Heart Against Diabetic CardiomyopathyDUSP8 Regulates Cardiac Ventricular Remodeling by Altering ERK1/2 Signaling.Altered gene expression patterns in muscle ring finger 1 null mice during denervation- and dexamethasone-induced muscle atrophy.DUSP-1 gene expression is not regulated by promoter methylation in diabetes-associated cardiac hypertrophy.Regulation of cardiac hypertrophy and remodeling through the dual-specificity MAPK phosphatases (DUSPs).Global MEF2 target gene analysis in cardiac and skeletal muscle reveals novel regulation of DUSP6 by p38MAPK-MEF2 signaling.Cardiac-restricted Overexpression of TRAF3 Interacting Protein 2 (TRAF3IP2) Results in Spontaneous Development of Myocardial Hypertrophy, Fibrosis, and Dysfunction.p38γ and δ promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation.Diet-induced obesity promotes altered remodeling and exacerbated cardiac hypertrophy following pressure overload.Phenotypic screening with human iPS cell-derived cardiomyocytes: HTS-compatible assays for interrogating cardiac hypertrophy.Inhibition of thyroid hormone receptor α1 impairs post-ischemic cardiac performance after myocardial infarction in mice.MicroRNA-200c modulates DUSP-1 expression in diabetes-induced cardiac hypertrophy.Elevated dual specificity protein phosphatase 4 in cardiomyopathy caused by lamin A/C gene mutation is primarily ERK1/2-dependent and its depletion improves cardiac function and survival.Toll-like receptor 5 deficiency exacerbates cardiac injury and inflammation induced by myocardial ischaemia-reperfusion in the mouse.
P2860
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P2860
Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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name
Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.
@en
Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.
@nl
type
label
Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.
@en
Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.
@nl
prefLabel
Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.
@en
Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.
@nl
P2093
P2860
P1433
P1476
Unrestrained p38 MAPK activation in Dusp1/4 double-null mice induces cardiomyopathy.
@en
P2093
Federica Accornero
John N Lorenz
Mannix Auger-Messier
Orlando F Bueno
Robert N Willette
Sanjeewa A Goonasekera
P2860
P356
10.1161/CIRCRESAHA.112.272963
P577
2012-09-19T00:00:00Z