Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.

Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.

Item
http://www.wikidata.org/entity/Q46038780
AmbrisentanKetoconazole-Associated Liver Injury in Drug-Drug Interaction Studies in Healthy Volunteers.High-performance liquid chromatography tandem mass spectrometry method for quantification of endothelin receptor antagonist drug, ambrisentan, in human plasma and its application in a pharmacokinetic study.Pharmacokinetic evaluation of ambrisentan.Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.Clinical pharmacokinetics and drug-drug interactions of endothelin receptor antagonists in pulmonary arterial hypertension.Efficacy, safety and clinical pharmacology of macitentan in comparison to other endothelin receptor antagonists in the treatment of pulmonary arterial hypertension.Interaction of ambrisentan with clarithromycin and its modulation by polymorphic SLCO1B1.Potential for pharmacokinetic interactions between ambrisentan and cyclosporine.Evaluation of the endothelin receptor antagonists ambrisentan, darusentan, bosentan, and sitaxsentan as substrates and inhibitors of hepatobiliary transporters in sandwich-cultured human hepatocytes.Investigation of the effects of ketoconazole on the pharmacokinetics of macitentan, a novel dual endothelin receptor antagonist, in healthy subjects.Safety and efficacy evaluation of ambrisentan in pulmonary hypertension.The effect of induction of CYP3A4 by St John's wort on ambrisentan plasma pharmacokinetics in volunteers of known CYP2C19 genotype.
P2860

Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.

Item
http://www.wikidata.org/entity/Q46038780
description
2009 nî lūn-bûn
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2009年の論文
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年学术文章
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2009年學術文章
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2009年學術文章
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name
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.
@en
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.
@nl
type
label
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.
@en
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.
@nl
prefLabel
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.
@en
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P356
P1433
P1476
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan.
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698