Phase 1 and pharmacokinetic study of LY3007113, a p38 MAPK inhibitor, in patients with advanced cancer.

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Phase 1 and pharmacokinetic study of LY3007113, a p38 MAPK inhibitor, in patients with advanced cancer.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

@zh-cn

2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

Phase 1 and pharmacokinetic st ...... patients with advanced cancer.

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Phase 1 and pharmacokinetic st ...... patients with advanced cancer.

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type

Item

label

Phase 1 and pharmacokinetic st ...... patients with advanced cancer.

@en

Phase 1 and pharmacokinetic st ...... patients with advanced cancer.

@nl

prefLabel

Phase 1 and pharmacokinetic st ...... patients with advanced cancer.

@en

Phase 1 and pharmacokinetic st ...... patients with advanced cancer.

@nl

P1476

Phase 1 and pharmacokinetic st ...... patients with advanced cancer

@en

P2093

Aaron Fink

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Amita Patnaik

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Anthony W Tolcher

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Ashwin Shahir

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Celine Pitou

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Daphne Farrington

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Edward M Chan

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Jonathan W Goldman

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Kyriakos Papadopoulos

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Lee S Rosen

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P2860

Inflammation and cancer: back to Virchow?

MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis

p38MAPK plays a crucial role in stromal-mediated tumorigenesis

Interleukin-1 and cancer progression: the emerging role of interleukin-1 receptor antagonist as a novel therapeutic agent in cancer treatment

LY2228820 dimesylate, a selective inhibitor of p38 mitogen-activated protein kinase, reduces angiogenic endothelial cord formation in vitro and in vivo.

p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage.

p38(MAPK): stress responses from molecular mechanisms to therapeutics.

Roles of p38 MAPKs in invasion and metastasis.

p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences: role in migration and invasion.

Targeting p38 MAPK inhibits multiple myeloma cell growth in the bone marrow milieu.

P2888

s10637-017-0532-2

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629-637

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scholarly article

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10.1007/S10637-017-0532-2

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P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Xuekui Zhang

P577

2017-12-01T00:00:00Z

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P698

29196957

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P932

6061137

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