The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells.
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The human forkhead protein FREAC-2 contains two functionally redundant activation domains and interacts with TBP and TFIIBGroucho binds two conserved regions of LEF-1 for HDAC-dependent repressionCloning and characterization of seven human forkhead proteins: binding site specificity and DNA bendingThe human LEF-1 gene contains a promoter preferentially active in lymphocytes and encodes multiple isoforms derived from alternative splicing.Differential importin-alpha recognition and nuclear transport by nuclear localization signals within the high-mobility-group DNA binding domains of lymphoid enhancer factor 1 and T-cell factor 1The HMG domain protein SSRP1/PREIIBF is involved in activation of the human embryonic beta-like globin gene.Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling.All Tcf HMG box transcription factors interact with Groucho-related co-repressorsExtensive alternative splicing and dual promoter usage generate Tcf-1 protein isoforms with differential transcription control propertiesRegulation of cell-type-specific interleukin-2 receptor alpha-chain gene expression: potential role of physical interactions between Elf-1, HMG-I(Y), and NF-kappa B family proteinsKu protein as a potential human T-cell leukemia virus type 1 (HTLV-1) Tax target in clastogenic chromosomal instability of mammalian cellsCell-context dependent TCF/LEF expression and function: alternative tales of repression, de-repression and activation potentialsDeterminants of DNA binding and bending by the Saccharomyces cerevisiae high mobility group protein NHP6A that are important for its biological activities. Role of the unique N terminus and putative intercalating methionine.Functional localization and competition between the androgen receptor and T-cell factor for nuclear beta-catenin: a means for inhibition of the Tcf signaling axisA possible role of catenin dyslocalization in pemphigus vulgaris pathogenesisThe nuclear localization signal of lymphoid enhancer factor-1 is recognized by two differentially expressed Srp1-nuclear localization sequence receptor proteinsInvolvement of SOX proteins in lens-specific activation of crystallin genesGATA-3: an unexpected regulator of cell lineage determination in skinStructural organization and promoter analysis of murine heat shock transcription factor-1 gene.Discovery of inhibitors of aberrant gene transcription from Libraries of DNA binding molecules: inhibition of LEF-1-mediated gene transcription and oncogenic transformation.Nmp4/CIZ: road block at the intersection of PTH and load.Cooperation among multiple transcription factors is required for access to minimal T-cell receptor alpha-enhancer chromatin in vivo.Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-cateninIn vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bendsThe notch intracellular domain can function as a coactivator for LEF-1The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse.TCF: Lady Justice casting the final verdict on the outcome of Wnt signalling.A possible role for the WNT-1 pathway in oral carcinogenesis.Looping mediated interaction between the promoter and 3' UTR regulates type II collagen expression in chondrocytes.An enhancer LEF-1/TCF-1 site is essential for insertion site-independent transgene expression in thymusNuclear endpoint of Wnt signaling: neoplastic transformation induced by transactivating lymphoid-enhancing factor 1.GRG5/AES interacts with T-cell factor 4 (TCF4) and downregulates Wnt signaling in human cells and zebrafish embryos.Past visits present: TCF/LEFs partner with ATFs for β-catenin-independent activitySignal- and development-dependent alternative splicing of LEF1 in T cells is controlled by CELF2.Functional interactions between Dlx2 and lymphoid enhancer factor regulate Msx2.Histone acetyltransferases regulate HIV-1 enhancer activity in vitro.A re-evaluation of two key reagents for in vivo studies of Wnt signaling.The peri-kappa B site mediates human immunodeficiency virus type 2 enhancer activation in monocytes but not in T cells.Sca-1 knockout impairs myocardial and cardiac progenitor cell function.PITX2 and beta-catenin interactions regulate Lef-1 isoform expression.
P2860
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P2860
The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh-hant
name
The hLEF/TCF-1 alpha HMG prote ...... TCR alpha enhancer in T cells.
@en
The hLEF/TCF-1 alpha HMG prote ...... TCR alpha enhancer in T cells.
@nl
type
label
The hLEF/TCF-1 alpha HMG prote ...... TCR alpha enhancer in T cells.
@en
The hLEF/TCF-1 alpha HMG prote ...... TCR alpha enhancer in T cells.
@nl
prefLabel
The hLEF/TCF-1 alpha HMG prote ...... TCR alpha enhancer in T cells.
@en
The hLEF/TCF-1 alpha HMG prote ...... TCR alpha enhancer in T cells.
@nl
P2093
P356
P1433
P1476
The hLEF/TCF-1 alpha HMG prote ...... TCR alpha enhancer in T cells.
@en
P2093
P304
P356
10.1101/GAD.7.12A.2418
P577
1993-12-01T00:00:00Z