Formation of steady-state oxygen gradients in vitro: application to liver zonation.
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Novel in vitro and mathematical models for the prediction of chemical toxicityVascular patterning sets the stage for macro and micro hepatic architectureAdvances in Engineered Liver Models for Investigating Drug-Induced Liver InjurySubstrate mediated enzyme prodrug therapyRepresentative Sinusoids for Hepatic Four-Scale Pharmacokinetics SimulationsFluid Dynamic Modeling to Support the Development of Flow-Based Hepatocyte Culture Systems for Metabolism StudiesA Microfabricated Platform for Generating Physiologically-Relevant Hepatocyte ZonationReal-time monitoring of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunctionNew advances in MR-compatible bioartificial liver.Cell viability viscoelastic measurement in a rheometer used to stress and engineer tissues at low sonic frequencies.Generation of oxygen gradients with arbitrary shapes in a microfluidic deviceComputerized microfluidic cell culture using elastomeric channels and Braille displaysEffect of oxygen concentration on viability and metabolism in a fluidized-bed bioartificial liver using ³¹P and ¹³C NMR spectroscopy.Modulating temporal and spatial oxygenation over adherent cellular culturesPolydimethylsiloxane-polycarbonate Microfluidic Devices for Cell Migration Studies Under Perpendicular Chemical and Oxygen Gradients.Synthesis, biophysical properties, and oxygenation potential of variable molecular weight glutaraldehyde-polymerized bovine hemoglobins with low and high oxygen affinity.Three-dimensional paper-based model for cardiac ischemiaBioreactor technologies to support liver function in vitro.Hemoglobin regulates the metabolic, synthetic, detoxification, and biotransformation functions of hepatoma cells cultured in a hollow fiber bioreactor.Toward modular biological models: defining analog modules based on referent physiological mechanisms.Oxygen gradients for open well cellular cultures via microfluidic substrates.Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies.A New Approach for On-Demand Generation of Various Oxygen Tensions for In Vitro Hypoxia ModelsPhosphorescent nanoparticles for quantitative measurements of oxygen profiles in vitro and in vivo.Organotypic liver culture models: meeting current challenges in toxicity testing.On the adhesion-cohesion balance and oxygen consumption characteristics of liver organoids.Studies of bacterial aerotaxis in a microfluidic device.A theoretical approach to zonation in a bioartificial liver.Directed oxygen gradients initiate a robust early remodeling response in engineered vascular graftsRecent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Towards high resolution analysis of metabolic flux in cells and tissues.Cell biology is different in small volumes: endogenous signals shape phenotype of primary hepatocytes cultured in microfluidic channels.Hypoxia promotes liver-stage malaria infection in primary human hepatocytes in vitro.Integration of in silico and in vitro platforms for pharmacokinetic-pharmacodynamic modeling.Engineered tissue grafts: opportunities and challenges in regenerative medicine.Bioreactor engineering of stem cell environmentsOxygen control with microfluidics.Insulin resistance in the liver: deficiency or excess of insulin?Microplatforms for gradient field generation of various properties and biological applications.3D liver models on a microplatform: well-defined culture, engineering of liver tissue and liver-on-a-chip.
P2860
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P2860
Formation of steady-state oxygen gradients in vitro: application to liver zonation.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
@zh
2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
@zh-sg
2003年學術文章
@yue
2003年學術文章
@zh-hant
name
Formation of steady-state oxygen gradients in vitro: application to liver zonation.
@en
Formation of steady-state oxygen gradients in vitro: application to liver zonation.
@nl
type
label
Formation of steady-state oxygen gradients in vitro: application to liver zonation.
@en
Formation of steady-state oxygen gradients in vitro: application to liver zonation.
@nl
prefLabel
Formation of steady-state oxygen gradients in vitro: application to liver zonation.
@en
Formation of steady-state oxygen gradients in vitro: application to liver zonation.
@nl
P356
P1476
Formation of steady-state oxygen gradients in vitro: application to liver zonation.
@en
P2093
Jared W Allen
Sangeeta N Bhatia
P304
P356
10.1002/BIT.10569
P577
2003-05-01T00:00:00Z