Mitochondrial decay in aging. Reversal through supplementation of acetyl-L-carnitine and N-tert-butyl-alpha-phenyl-nitrone.
about
Memory loss in old rats is associated with brain mitochondrial decay and RNA/DNA oxidation: partial reversal by feeding acetyl-L-carnitine and/or R-alpha -lipoic acidOxidative-stress-dependent up-regulation of Bcl-2 expression in the central nervous system of aged Fisher-344 rats.Age-related decline in mitochondrial bioenergetics: does supercomplex destabilization determine lower oxidative capacity and higher superoxide production?Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress.Age-associated mitochondrial oxidative decay: improvement of carnitine acetyltransferase substrate-binding affinity and activity in brain by feeding old rats acetyl-L- carnitine and/or R-alpha -lipoic acid.Acetyl-L-carnitine supplementation reverses the age-related decline in carnitine palmitoyltransferase 1 (CPT1) activity in interfibrillar mitochondria without changing the L-carnitine content in the rat heartPotential therapeutic benefits of strategies directed to mitochondria.Development of lipophilic cations as therapies for disorders due to mitochondrial dysfunction.Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites.A2E and blue light in the retina: the paradigm of age-related macular degeneration.Ethanol feeding enhances age-related deterioration of the rat hepatic mitochondrionThe functions of cardiolipin in cellular metabolism-potential modifiers of the Barth syndrome phenotypePhenyl-alpha-tert-butyl nitrone reverses mitochondrial decay in acute Chagas' disease.Supercomplexes of the mitochondrial electron transport chain decline in the aging rat heart.Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles.Organochalcogens inhibit mitochondrial complexes I and II in rat brain: possible implications for neurotoxicity.Mitochondrial oxygen metabolism in primary human lens epithelial cells: Association with age, diabetes and glaucoma.Gene expression profiling of aging in multiple mouse strains: identification of aging biomarkers and impact of dietary antioxidants.Insight into age-related macular degeneration: new vision in sight.Changes in markers of oxidative stress and membrane properties in synaptosomes from rats exposed prenatally to toluene.Regulation of tissue oxygen levels in the mammalian lens.
P2860
Q24530352-035818C3-3991-41BF-A576-B7B042941622Q31962000-24DF3662-572C-4780-BE83-792CFA340BC9Q33897468-4D38CC7D-E099-4CB8-8AB6-84D455BF8160Q34011395-8168D5DB-513D-43CD-8B10-C89574709314Q34011426-26BE1B93-30B9-41BC-870E-EE9BDADB07E7Q34102948-263EA04B-BE8F-443F-9C5F-86C451993C64Q34117168-E63EEFD5-9183-4BF5-BBBD-59CF86343097Q34452604-F305EE6A-0AE5-4C7B-A3AC-BA8F33EC00A5Q34614478-DC1B281E-2623-4BD2-B518-E9C1F03CABC8Q34658953-6C4672BF-024A-4C23-8C87-A73A225AACF9Q35126800-695CC436-06FD-4690-8934-CFF0A9C682E7Q35128445-54937FD1-A6E4-4A05-8165-B9443899B10EQ35569849-FCB50368-BC96-48BC-A731-D648050A71D2Q37388302-B7FAA464-6359-4B81-A453-5C380881E4E1Q37456323-BABC49B0-0D18-4681-ABC1-58F204A31EDDQ37601925-098F53FC-0AC4-4B89-8E9E-946FEA593E0CQ41242669-E09456F1-9843-409A-B923-219CA988D19CQ41866466-C6E4E5C0-3CF0-4C4B-89D7-E16475DCA93CQ43586539-643DDCDE-C4DF-4E76-B4D0-261F2EC7333DQ43989269-ED572460-AF19-4DF6-9D32-8E04E23ED37EQ44991686-5CB5795B-BD1D-41AA-BEDE-33571DD758D0
P2860
Mitochondrial decay in aging. Reversal through supplementation of acetyl-L-carnitine and N-tert-butyl-alpha-phenyl-nitrone.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Mitochondrial decay in aging. ...... rt-butyl-alpha-phenyl-nitrone.
@en
Mitochondrial decay in aging. ...... rt-butyl-alpha-phenyl-nitrone.
@nl
type
label
Mitochondrial decay in aging. ...... rt-butyl-alpha-phenyl-nitrone.
@en
Mitochondrial decay in aging. ...... rt-butyl-alpha-phenyl-nitrone.
@nl
prefLabel
Mitochondrial decay in aging. ...... rt-butyl-alpha-phenyl-nitrone.
@en
Mitochondrial decay in aging. ...... rt-butyl-alpha-phenyl-nitrone.
@nl
P2093
P1476
Mitochondrial decay in aging. ...... rt-butyl-alpha-phenyl-nitrone.
@en
P2093
P304
P356
10.1111/J.1749-6632.1998.TB09904.X
P407
P577
1998-11-01T00:00:00Z