The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation.
about
Autophagy in the physiology and pathology of the central nervous systemExecution of RIPK3-regulated necrosisNecrotic Cells Actively Attract Phagocytes through the Collaborative Action of Two Distinct PS-Exposure MechanismsIdentification of Ppk26, a DEG/ENaC Channel Functioning with Ppk1 in a Mutually Dependent Manner to Guide Locomotion Behavior in Drosophila.Annexin II light chain p11 promotes functional expression of acid-sensing ion channel ASIC1aExposure of phosphatidylserine on the cell surfaceProfiling a Caenorhabditis elegans behavioral parametric dataset with a supervised K-means clustering algorithm identifies genetic networks regulating locomotion.The Xenopus oocyte: a single-cell model for studying Ca2+ signaling.Noncanonical cell death in the nematode Caenorhabditis elegans.Acidosis, acid-sensing ion channels, and neuronal cell death.Specific roles for DEG/ENaC and TRP channels in touch and thermosensation in C. elegans nociceptors.Mechanosensitive unpaired innexin channels in C. elegans touch neurons.In vivo neuronal calcium imaging in C. elegans.Second transmembrane domain modulates epithelial sodium channel gating in response to shear stressMechanism of pyrethroid pesticide-induced apoptosis: role of calpain and the ER stress pathwaySTR-33, a novel G protein-coupled receptor that regulates locomotion and egg laying in Caenorhabditis elegansSensory functions for degenerin/epithelial sodium channels (DEG/ENaC).Key note lecture: toward a mechanistic taxonomy for cell death programs.Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegansThe Apoptotic Engulfment Machinery Regulates Axonal Degeneration in C. elegans Neurons.Vacuolar H+-ATPase (V-ATPase) promotes vacuolar membrane permeabilization and nonapoptotic death in stressed yeastFunction of a STIM1 homologue in C. elegans: evidence that store-operated Ca2+ entry is not essential for oscillatory Ca2+ signaling and ER Ca2+ homeostasis.Hyperactivation of the mammalian degenerin MDEG promotes caspase-8 activation and apoptosis.MEC-2 and MEC-6 in the Caenorhabditis elegans sensory mechanotransduction complex: auxiliary subunits that enable channel activityMEC-10 and MEC-19 Reduce the Neurotoxicity of the MEC-4(d) DEG/ENaC Channel in Caenorhabditis elegans.A glial DEG/ENaC channel functions with neuronal channel DEG-1 to mediate specific sensory functions in C. elegansTwo novel DEG/ENaC channel subunits expressed in glia are needed for nose-touch sensitivity in Caenorhabditis elegans.Neurotoxic unc-8 mutants encode constitutively active DEG/ENaC channels that are blocked by divalent cations.Activation of the Caenorhabditis elegans Degenerin Channel by Shear Stress Requires the MEC-10 Subunit.Extracellular zinc and ATP-gated P2X receptor calcium entry channels: New zinc receptors as physiological sensors and therapeutic targetsNoncanonical cell death programs in the nematode Caenorhabditis elegans.Modeling molecular and cellular aspects of human disease using the nematode Caenorhabditis elegans.ASIC1 contributes to pulmonary vascular smooth muscle store-operated Ca(2+) entry.Insights into the molecular determinants of proton inhibition in an acid-inactivated degenerins and mammalian epithelial Na(+) channel.A novel benzofuran derivative, ACDB, induces apoptosis of human chondrosarcoma cells through mitochondrial dysfunction and endoplasmic reticulum stress.Progressive degeneration of dopaminergic neurons through TRP channel-induced cell death.NRA-2, a nicalin homolog, regulates neuronal death by controlling surface localization of toxic Caenorhabditis elegans DEG/ENaC channels.Smooth muscle acid-sensing ion channel 1: pathophysiological implication in hypoxic pulmonary hypertension.Endogenous recovery after brain damage: molecular mechanisms that balance neuronal life/death fate.Knock-out of a mitochondrial sirtuin protects neurons from degeneration in Caenorhabditis elegans.
P2860
Q27000701-F0CA5478-75CA-4D63-AA34-09DB22D1A33FQ27022081-922DE26B-B3B3-4C90-AE8C-93092E163B9EQ27311005-5C499432-7F13-4FE3-8915-2C39DF605978Q27321382-47541E1F-CF23-4F52-86BD-902A7EFA2AA0Q28272902-7C982E32-CBF0-4723-AB5A-AED01739BB99Q28386869-2C6C9D7A-4BAD-4B19-B0F7-6858FCB5F508Q30499947-E455C37F-DB14-4787-B8EB-FA4A75175F07Q33595920-5BA8E790-8F44-4BB8-9A4B-63531E9DB8A1Q33973337-F3CA7DA2-E888-4D27-8A87-4AD8C07000EDQ34217798-645A385E-39CD-483A-8809-9D777D1309DEQ34284827-D2282C42-F877-4C49-AA6F-79E3B1D20B02Q34519112-5648F665-CA90-4336-A18E-770FA81BB47BQ34679531-BB66F43C-E50D-4F1D-BE9A-A62AFD911BE3Q34979677-E0C0C26D-8B39-40F3-8798-D34B5FA1644BQ35161421-E3689F8D-1A6D-4E20-BE04-C9B1A5C6499CQ35562769-9FC114D1-6E34-45D1-98F1-584B165FBAE0Q35819038-0A16DA3F-7945-44B6-B04E-4D68FC28C865Q35828412-A6CF20A9-848B-4EE0-B93C-AB3207B4FE82Q35844548-422CDBB5-4514-4CF5-BAC8-01A7C3921620Q35923582-DCF4B97B-1EFA-48C3-9E83-E745B2B34F75Q36003655-FC11AAB3-CDF7-49B2-9612-2CD2BFC847ECQ36295832-C1449BA1-6B4D-4DAB-B096-BCE9D84AC2A5Q36579435-038BB5FF-8681-4909-B815-BE8C9D788082Q36667903-FC5928FE-E539-4129-AA76-3F2C97112356Q36780861-8DD9BBF2-ABB9-4F7D-B47E-899C16DE17D5Q36891446-0A225CC0-C0EB-460C-B0E3-7FF8A6C0BBB2Q37013669-B8D97425-54E1-4732-A0CC-88C3494510E2Q37055480-56677AAF-966A-487A-B7D9-A32592D34689Q37065695-535EF325-674E-4664-B21A-5DAF8DFF3203Q37135566-69D5D257-B547-4001-BA7F-1DC57B96B5E9Q37147746-4758BB32-1999-41D9-A533-409032C87A77Q37293096-32F05ACC-51B3-4CC2-862D-1EE3DBEAD213Q37343898-C8004209-62FF-48D2-9597-6D4EE7FF61A2Q37394153-3352F89C-5038-4CED-BEAF-F0780BB6E08BQ37696338-022BC880-793E-4AE7-9805-3EFDD2649C54Q37717607-E8F81A37-F7FE-4A9D-9245-2AF2DC4F67D6Q37727615-92A29287-4676-4E4E-81B7-E74740C0DEDFQ38268355-70F88FD5-FBAA-4966-8228-B3F4684D189FQ38587925-99742177-DABC-420B-957A-DBC533DF2167Q38618355-0F7A7E36-6971-4EEC-8D76-2708841D5E07
P2860
The neurotoxic MEC-4(d) DEG/ENaC sodium channel conducts calcium: implications for necrosis initiation.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年学术文章
@wuu
2004年学术文章
@zh
2004年学术文章
@zh-cn
2004年学术文章
@zh-hans
2004年学术文章
@zh-my
2004年学术文章
@zh-sg
2004年學術文章
@yue
2004年學術文章
@zh-hant
name
The neurotoxic MEC-4
@nl
The neurotoxic MEC-4(d) DEG/EN ...... tions for necrosis initiation.
@en
type
label
The neurotoxic MEC-4
@nl
The neurotoxic MEC-4(d) DEG/EN ...... tions for necrosis initiation.
@en
prefLabel
The neurotoxic MEC-4
@nl
The neurotoxic MEC-4(d) DEG/EN ...... tions for necrosis initiation.
@en
P2093
P2860
P356
P1433
P1476
The neurotoxic MEC-4(d) DEG/EN ...... tions for necrosis initiation.
@en
P2093
Beate Gerstbrein
Christian Frøkjaer-Jensen
Dewey C Royal
Gargi Mukherjee
Laura Bianchi
Mary Anne Royal
William R Schafer
P2860
P2888
P304
P356
10.1038/NN1347
P407
P577
2004-11-07T00:00:00Z