Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia.
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Uric acid, hyperuricemia and vascular diseasesThe novel ATP-sensitive potassium channel opener iptakalim prevents insulin resistance associated with hypertension via restoring endothelial function.Pharmacologic targeting ERK1/2 attenuates the development and progression of hyperuricemic nephropathy in rats.Effects of dietary creatine supplementation on systemic microvascular density and reactivity in healthy young adultsEGF Receptor Inhibition Alleviates Hyperuricemic Nephropathy.Mutational analysis of the Kir6.1 gene in Chinese hypertensive patients treated with the novel ATP-sensitive potassium channel opener iptakalim.Iptakalim, a novel ATP-sensitive potassium channel opener, inhibits pulmonary arterial smooth muscle cell proliferation by downregulation of PKC-α.Lower Serum Levels of Uric Acid in Uterine Fibroids and Fibrocystic Breast Disease Patients in Dongying City, China.Combination of captopril and allopurinol retards fructose-induced metabolic syndrome.Chemerin/ChemR23 signaling axis is involved in the endothelial protection by K(ATP) channel opener iptakalim.Association of the antihypertensive response of iptakalim with KCNJ11 (Kir6.2 gene) polymorphisms in Chinese Han hypertensive patients.Soluble uric acid increases intracellular calcium through an angiotensin II-dependent mechanism in immortalized human mesangial cells.Transforming growth factor-β1/Smad3-independent epithelial-mesenchymal transition in type I collagen glomerulopathy.Iptakalim ameliorates monocrotaline-induced pulmonary arterial hypertension in rats.Febuxostat attenuates ER stress mediated kidney injury in a rat model of hyperuricemic nephropathy.Single-dose pharmacokinetics and safety of iptakalim hydrochloride in Chinese healthy volunteers.
P2860
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P2860
Activation of ATP-sensitive potassium channels protects vascular endothelial cells from hypertension and renal injury induced by hyperuricemia.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Activation of ATP-sensitive po ...... jury induced by hyperuricemia.
@en
Activation of ATP-sensitive po ...... jury induced by hyperuricemia.
@nl
type
label
Activation of ATP-sensitive po ...... jury induced by hyperuricemia.
@en
Activation of ATP-sensitive po ...... jury induced by hyperuricemia.
@nl
prefLabel
Activation of ATP-sensitive po ...... jury induced by hyperuricemia.
@en
Activation of ATP-sensitive po ...... jury induced by hyperuricemia.
@nl
P2093
P1476
Activation of ATP-sensitive po ...... jury induced by hyperuricemia.
@en
P2093
Chao-Liang Long
Guo-Shu Liu
Wen-Yu Cui
Xiu-Chuan Qin
Yan-Fang Zhang
Zhi-Yuan Pan
P304
P356
10.1097/HJH.0B013E328312C8C1
P577
2008-12-01T00:00:00Z