Leveraging Humanized Animal Models to Understand Human Drug Disposition: Opportunities, Challenges, and Future Directions.

about

Leveraging Humanized Animal Models to Understand Human Drug Disposition: Opportunities, Challenges, and Future Directions.

Item

http://www.wikidata.org/entity/Q46250508

description

2017 nî lūn-bûn

@nan

2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh

2017年學術文章

@zh-hant

name

Leveraging Humanized Animal Mo ...... lenges, and Future Directions.

@en

Leveraging Humanized Animal Mo ...... lenges, and Future Directions.

@nl

type

Item

label

Leveraging Humanized Animal Mo ...... lenges, and Future Directions.

@en

Leveraging Humanized Animal Mo ...... lenges, and Future Directions.

@nl

prefLabel

Leveraging Humanized Animal Mo ...... lenges, and Future Directions.

@en

Leveraging Humanized Animal Mo ...... lenges, and Future Directions.

@nl

P1476

Leveraging Humanized Animal Mo ...... lenges, and Future Directions.

@en

P2093

Edna F Choo

http://www.w3.org/2001/XMLSchema#string

Laurent Salphati

http://www.w3.org/2001/XMLSchema#string

P2860

Mice as clinically relevant models for the study of cytochrome P450-dependent metabolism.

Evaluation of Cytochrome P450 3A4-Mediated Drug-Drug Interaction Potential for Cobimetinib Using Physiologically Based Pharmacokinetic Modeling and Simulation.

Use of transgenic mouse models to understand the oral disposition and drug-drug interaction potential of cobimetinib, a MEK inhibitor.

Absolute bioavailability and effect of formulation change, food, or elevated pH with rabeprazole on cobimetinib absorption in healthy subjects.

P31

scholarly article

P356

10.1002/CPT.908

http://www.w3.org/2001/XMLSchema#string

P407

English

P577

2017-11-28T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29193027

http://www.w3.org/2001/XMLSchema#string