A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.
about
Links between Human LINE-1 Retrotransposons and Hepatitis Virus-Related Hepatocellular CarcinomaMutations, kataegis and translocations in B cells: understanding AID promiscuous activityAssociations between activation-induced cytidine deaminase/apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like cytidine deaminase expression, hepatitis B virus (HBV) replication and HBV-associated liver disease (Review)Immunity, Inflammation, and CancerA high level of liver-specific expression of oncogenic Kras(V12) drives robust liver tumorigenesis in transgenic zebrafishActivation-induced cytidine deaminase expression in CD4+ T cells is associated with a unique IL-10-producing subset that increases with ageHsa-miR-520d induces hepatoma cells to form normal liver tissues via a stemness-mediated process.Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis.Inflammation and oncogenesis: a vicious connection.Clustered and genome-wide transient mutagenesis in human cancers: Hypermutation without permanent mutators or loss of fitnessInnate immune signaling induces high levels of TC-specific deaminase activity in primary monocyte-derived cells through expression of APOBEC3A isoformsIn vivo analysis of Aicda gene regulation: a critical balance between upstream enhancers and intronic silencers governs appropriate expression.Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism.NF-κB and cancer: a paradigm of Yin-Yang.Chronic lung injury by constitutive expression of activation-induced cytidine deaminase leads to focal mucous cell metaplasia and cancer.Development of a High-Throughput Molecular Imaging-Based Orthotopic Hepatocellular Carcinoma ModelAID-expressing epithelium is protected from oncogenic transformation by an NKG2D surveillance pathway.Involvement of activation-induced cytidine deaminase in skin cancer developmentAPOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotionActivation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous CarcinogenesisMalignant B-cell intra-clonal diversification: following the yarn in the labyrinth.Hormones and AID: balancing immunity and autoimmunity.Sequential analysis of diethylnitrosamine-induced hepatocarcinogenesis in rats.Targeting activation-induced cytidine deaminase overcomes tumor evasion of immunotherapy by CTLs.Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A.Acquisition of Genetic Aberrations by Activation-Induced Cytidine Deaminase (AID) during Inflammation-Associated Carcinogenesis.AID Biology: A pathological and clinical perspective.Activation-induced cytidine deaminase is dispensable for virus-mediated liver and skin tumor development in mouse models.Potential therapeutic targets of TP53 gene in the context of its classically canonical functions and its latest non-canonical functions in human cancer.
P2860
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P2860
A novel mouse model of hepatocarcinogenesis triggered by AID causing deleterious p53 mutations.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
A novel mouse model of hepatoc ...... ing deleterious p53 mutations.
@en
A novel mouse model of hepatoc ...... ing deleterious p53 mutations.
@nl
type
label
A novel mouse model of hepatoc ...... ing deleterious p53 mutations.
@en
A novel mouse model of hepatoc ...... ing deleterious p53 mutations.
@nl
prefLabel
A novel mouse model of hepatoc ...... ing deleterious p53 mutations.
@en
A novel mouse model of hepatoc ...... ing deleterious p53 mutations.
@nl
P2093
P2860
P356
P1433
P1476
A novel mouse model of hepatoc ...... sing deleterious p53 mutations
@en
P2093
H Marusawa
K Kinoshita
T Toyoshima
Y Kitawaki
P2860
P2888
P304
P356
10.1038/ONC.2008.415
P407
P577
2008-11-10T00:00:00Z