Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.

Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.

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http://www.wikidata.org/entity/Q46286339
2-(4-(Biphenyl-4-ylamino)-6-chloropyrimidin-2-ylthio)octanoic acid (HZ52)--a novel type of 5-lipoxygenase inhibitor with favourable molecular pharmacology and efficacy in vivoEffect of a 5-lipoxygenase inhibitor on leukotriene generation and airway responses after allergen challenge in asthmatic patientsSuppression of inflammatory responses to 12-O-tetradecanoyl-phorbol-13-acetate and carrageenin by YM-26734, a selective inhibitor of extracellular group II phospholipase A2In vivo pharmacological evaluation of compound 48/80-induced airways oedema by MRI.Inhibition of leukotriene release in anaphylactic guinea-pig hearts by a 5-lipoxygenase inhibitor, CGS 8515.Calcium ionophore (A-23187) induced peritoneal eicosanoid biosynthesis: a rapid method to evaluate inhibitors of arachidonic acid metabolism in vivo.CGS 22745: a selective orally active inhibitor of 5-lipoxygenase.CGS 26529: the biological profile of a novel, orally active 5-lipoxygenase inhibitor with an extended duration of action.Leukotriene biosynthesis inhibition by aryl and aroyl substituted naphthoquinones.Role of arachidonic acid metabolites in airway responses induced by trimellitic anhydride in actively sensitized guinea pigs.Attenuation of inhaled allergen-induced airway microvascular leakage and airflow obstruction in guinea pigs by a 5-lipoxygenase inhibitor (A-63162).
P2860

Characterization of CGS 8515 as a selective 5-lipoxygenase inhibitor using in vitro and in vivo models.

Item
http://www.wikidata.org/entity/Q46286339
description
1988 nî lūn-bûn
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1988年の論文
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1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年學術文章
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1988年學術文章
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name
Characterization of CGS 8515 a ...... g in vitro and in vivo models.
@en
Characterization of CGS 8515 a ...... g in vitro and in vivo models.
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type
label
Characterization of CGS 8515 a ...... g in vitro and in vivo models.
@en
Characterization of CGS 8515 a ...... g in vitro and in vivo models.
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prefLabel
Characterization of CGS 8515 a ...... g in vitro and in vivo models.
@en
Characterization of CGS 8515 a ...... g in vitro and in vivo models.
@nl
P1433
P1476
P2093
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P433
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Characterization of CGS 8515 a ...... g in vitro and in vivo models.
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P2093
P304
P31
P356
10.1016/0005-2760(88)90207-X
P433
P478
P577
P698