The Q121 variant of ENPP1 may protect from childhood overweight/obesity in the Italian population.

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Genomic insights into early-onset obesity.

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The Q121 variant of ENPP1 may protect from childhood overweight/obesity in the Italian population.

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2008 nî lūn-bûn

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The Q121 variant of ENPP1 may ...... ity in the Italian population.

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The Q121 variant of ENPP1 may ...... ity in the Italian population.

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The Q121 variant of ENPP1 may ...... ity in the Italian population.

@en

The Q121 variant of ENPP1 may ...... ity in the Italian population.

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The Q121 variant of ENPP1 may ...... ity in the Italian population.

@en

The Q121 variant of ENPP1 may ...... ity in the Italian population.

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The Q121 variant of ENPP1 may ...... ity in the Italian population.

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Anita Morandi

http://www.w3.org/2001/XMLSchema#string

Antonio Petrone

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David Meyre

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Leonardo Pinelli

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Vincent Vatin

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The Q allele variant (GLN121) of membrane glycoprotein PC-1 interacts with the insulin receptor and inhibits insulin signaling more effectively than the common K allele variant (LYS121)

Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus

Establishing a standard definition for child overweight and obesity worldwide: international survey

Membrane glycoprotein PC-1 inhibition of insulin receptor function occurs via direct interaction with the receptor alpha-subunit

Genetics of obesity and type 2 diabetes: tracking pathogenic traits during the predisease period.

Haplotype structure of the ENPP1 Gene and Nominal Association of the K121Q missense single nucleotide polymorphism with glycemic traits in the Framingham Heart Study.

The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: evidence from an updated meta-analysis in 42,042 subjects.

Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes.

Homozygosity of the Pro12Ala variant of the peroxisome proliferation-activated receptor-gamma2 (PPAR-gamma2): divergent modulating effects on body mass index in obese and lean Caucasian men.

Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.

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202-206

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scholarly article

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10.1038/OBY.2008.470

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Philippe Froguel

Raffaella Buzzetti

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2008-10-23T00:00:00Z

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23412813

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18948963

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P921

Adipositas

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The Q121 variant of ENPP1 may protect from childhood overweight/obesity in the Italian population.

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P2860

P2860

The Q121 variant of ENPP1 may protect from childhood overweight/obesity in the Italian population.

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P1433

P1476

P2093

P2860

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P31

P356

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P2860

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P31

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