Species-related exposure of phase II metabolite gemfibrozil 1-O-β-glucuronide between human and mice: A net induction of mouse P450 activity was revealed.

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Species-related exposure of phase II metabolite gemfibrozil 1-O-β-glucuronide between human and mice: A net induction of mouse P450 activity was revealed.

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2017 nî lūn-bûn

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Species-related exposure of ph ...... se P450 activity was revealed.

@en

Species-related exposure of ph ...... se P450 activity was revealed.

@nl

type

Item

label

Species-related exposure of ph ...... se P450 activity was revealed.

@en

Species-related exposure of ph ...... se P450 activity was revealed.

@nl

prefLabel

Species-related exposure of ph ...... se P450 activity was revealed.

@en

Species-related exposure of ph ...... se P450 activity was revealed.

@nl

P1476

Species-related exposure of ph ...... use P450 activity was revealed

@en

P2093

Aiming Liu

http://www.w3.org/2001/XMLSchema#string

Hante Lin

http://www.w3.org/2001/XMLSchema#string

Jiao Lin

http://www.w3.org/2001/XMLSchema#string

Julin Yang

http://www.w3.org/2001/XMLSchema#string

Manyun Dai

http://www.w3.org/2001/XMLSchema#string

Minzhu Xie

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P2860

Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

Pregnane X receptor-mediated induction of Cyp3a by black cohosh.

Gemfibrozil greatly increases plasma concentrations of cerivastatin.

Drug-drug interaction between pitavastatin and various drugs via OATP1B1.

Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug inter

PPARalpha agonist-induced rodent tumors: modes of action and human relevance.

The PPAR alpha-humanized mouse: a model to investigate species differences in liver toxicity mediated by PPAR alpha.

CYP2C8 Is a Novel Target of Peroxisome Proliferator-Activated Receptor α in Human Liver.

Hepatic uptake of atorvastatin: influence of variability in transporter expression on uptake clearance and drug-drug interactions.

Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide.

P304

535-542

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P31

scholarly article

P356

10.1002/BDD.2105

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Min Luo

P577

2017-11-20T00:00:00Z

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P698

28946176

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P921

gemfibrozil