Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts.
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Registered report: Widespread potential for growth factor-driven resistance to anticancer kinase inhibitorsEstablishment and characterization of a novel ovarian serous adenocarcinoma cell line, TU-OS-4, that overexpresses EGFR and HER2.A recombinant decoy comprising EGFR and ErbB-4 inhibits tumor growth and metastasis.Rational optimization of a bispecific ligand trap targeting EGF receptor family ligands.Signal integration: a framework for understanding the efficacy of therapeutics targeting the human EGFR familyHER3/ErbB3, an emerging cancer therapeutic target.Fcγ1 fragment of IgG1 as a powerful affinity tag in recombinant Fc-fusion proteins: immunological, biochemical and therapeutic properties.Overcoming acquired resistance to cetuximab by dual targeting HER family receptors with antibody-based therapyLigand binding induces a conformational change in epidermal growth factor receptor dimers.A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation.Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade.A truncated soluble epidermal growth factor receptor-Fc fusion ligand trap displays anti-tumour activity in vivo.Electrohydrodynamic-Induced SERS Immunoassay for Extensive Multiplexed Biomarker Sensing.
P2860
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P2860
Human epidermal growth factor receptor (HER-1:HER-3) Fc-mediated heterodimer has broad antiproliferative activity in vitro and in human tumor xenografts.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Human epidermal growth factor ...... and in human tumor xenografts.
@en
type
label
Human epidermal growth factor ...... and in human tumor xenografts.
@en
prefLabel
Human epidermal growth factor ...... and in human tumor xenografts.
@en
P2093
P1476
Human epidermal growth factor ...... and in human tumor xenografts.
@en
P2093
Brett Jorgensen
Cathleen Brdlik
Francis W Lau
H Michael Shepard
James Rozzelle
Jeffrey N Higaki
Juan Zhang
P304
P356
10.1158/1535-7163.MCT-07-2151
P577
2008-10-01T00:00:00Z