Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation.
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The nuclear envelopathies and human diseasesEmerin-prelamin A interplay in human fibroblastsMolecular insights into the premature aging disease progeriaThree-Dimensional Analysis of Cell Division Orientation in Epidermal Basal Layer Using Intravital Two-Photon MicroscopyCytoskeletal tension induces the polarized architecture of the nucleus.Lamina-associated polypeptide (LAP)2α and other LEM proteins in cancer biologyRecent advances in understanding the role of lamins in health and diseasePhysiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear EdgeEmbryonic senescence and laminopathies in a progeroid zebrafish modelMonoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482WNovel phosphotyrosine targets of FGFR2IIIb signaling.Lamina-associated polypeptide 2alpha loss impairs heart function and stress response in mice.Another broken heart: loss of lamina-associated polypeptide 2alpha causes systolic dysfunction.Lamin-binding ProteinsMitotic defects lead to pervasive aneuploidy and accompany loss of RB1 activity in mouse LmnaDhe dermal fibroblastsPalifermin for the protection and regeneration of epithelial tissues following injury: new findings in basic research and pre-clinical models.Alternative splicing and co-option of transposable elements: the case of TMPO/LAP2α and ZNF451 in mammals.Nuclear lamins: key regulators of nuclear structure and activitiesNetworking in the nucleus: a spotlight on LEM-domain proteinsNuclear membrane diversity: underlying tissue-specific pathologies in disease?Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype.Lamins at a glance.Progerin reduces LAP2α-telomere association in Hutchinson-Gilford progeria.The cellular mastermind(?)-mechanotransduction and the nucleus.Nuclear mechanics in diseaseMechanics of the nucleus.Proliferation of progeria cells is enhanced by lamina-associated polypeptide 2α (LAP2α) through expression of extracellular matrix proteinsLamins in development, tissue maintenance and stress.Lamin B1 fluctuations have differential effects on cellular proliferation and senescence.High mobility group protein N5 (HMGN5) and lamina-associated polypeptide 2α (LAP2α) interact and reciprocally affect their genome-wide chromatin organization.Muscle development, regeneration and laminopathies: how lamins or lamina-associated proteins can contribute to muscle development, regeneration and disease.Lamins regulate cell trafficking and lineage maturation of adult human hematopoietic cells.Defective skeletal muscle growth in lamin A/C-deficient mice is rescued by loss of Lap2α.Tissue specificity in the nuclear envelope supports its functional complexity.Chrom3D: three-dimensional genome modeling from Hi-C and nuclear lamin-genome contacts.The laminA/NF-Y protein complex reveals an unknown transcriptional mechanism on cell proliferationThe search for evolutionary developmental origins of aging in zebrafish: a novel intersection of developmental and senescence biology in the zebrafish model system.Prelamin A-mediated nuclear envelope dynamics in normal and laminopathic cells.Nuclear envelope influences on cell-cycle progression.Nuclear lamina at the crossroads of the cytoplasm and nucleus.
P2860
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P2860
Loss of nucleoplasmic LAP2alpha-lamin A complexes causes erythroid and epidermal progenitor hyperproliferation.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Loss of nucleoplasmic LAP2alph ...... progenitor hyperproliferation.
@en
Loss of nucleoplasmic LAP2alph ...... progenitor hyperproliferation.
@nl
type
label
Loss of nucleoplasmic LAP2alph ...... progenitor hyperproliferation.
@en
Loss of nucleoplasmic LAP2alph ...... progenitor hyperproliferation.
@nl
prefLabel
Loss of nucleoplasmic LAP2alph ...... progenitor hyperproliferation.
@en
Loss of nucleoplasmic LAP2alph ...... progenitor hyperproliferation.
@nl
P2093
P50
P356
P1433
P1476
Loss of nucleoplasmic LAP2alph ...... progenitor hyperproliferation.
@en
P2093
Colin L Stewart
Daniela Dorner
Ivana Gotic
Marc A Kerenyi
Peter Fuchs
Reginald Bittner
Rosana Kral
Serguei Kozlov
Tatiana V Cohen
P2888
P304
P356
10.1038/NCB1793
P577
2008-10-12T00:00:00Z