Opening of the ADP-bound active site in the ABC transporter ATPase dimer: evidence for a constant contact, alternating sites model for the catalytic cycle.
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Visualizing functional motions of membrane transporters with molecular dynamics simulationsInter-domain communication mechanisms in an ABC importer: a molecular dynamics study of the MalFGK2E complexInsights into How Nucleotide-Binding Domains Power ABC TransportKinetics of the Association/Dissociation Cycle of an ATP-binding Cassette Nucleotide-binding DomainThe Nucleotide-Free State of the Multidrug Resistance ABC Transporter LmrA: Sulfhydryl Cross-Linking Supports a Constant Contact, Head-to-Tail Configuration of the Nucleotide-Binding DomainsStructural consequences of ATP hydrolysis on the ABC transporter NBD dimer: molecular dynamics studies of HlyB.Asymmetric switching in a homodimeric ABC transporter: a simulation studyStable ATP binding mediated by a partial NBD dimer of the CFTR chloride channelAn asymmetric post-hydrolysis state of the ABC transporter ATPase dimer.Mutant cycles at CFTR's non-canonical ATP-binding site support little interface separation during gatingMolecular-dynamics simulations of the ATP/apo state of a multidrug ATP-binding cassette transporter provide a structural and mechanistic basis for the asymmetric occluded stateDissociation of ATP-binding cassette nucleotide-binding domain dimers into monomers during the hydrolysis cycleThree-dimensional structure of the human breast cancer resistance protein (BCRP/ABCG2) in an inward-facing conformation.ATP Hydrolysis Induced Conformational Changes in the Vitamin B12 Transporter BtuCD Revealed by MD Simulations.Phorbol 12-myristate 13-acetate inhibits P-glycoprotein-mediated efflux of digoxin in MDCKII-MDR1 and Caco-2 cell monolayer models.Dynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stabilityMolecular organization and ATP-induced conformational changes of ABCA4, the photoreceptor-specific ABC transporterAssociation/dissociation of the nucleotide-binding domains of the ATP-binding cassette protein MsbA measured during continuous hydrolysisMolecular dynamics simulations of membrane channels and transportersHydrolysis at one of the two nucleotide-binding sites drives the dissociation of ATP-binding cassette nucleotide-binding domain dimers.Structure of ABC transporters.Mechanism of the ABC transporter ATPase domains: catalytic models and the biochemical and biophysical record.A reciprocating twin-channel model for ABC transporters.The Lipid Bilayer Modulates the Structure and Function of an ATP-binding Cassette ExporterCoupled ATPase-adenylate kinase activity in ABC transporters.Release of Entropic Spring Reveals Conformational Coupling Mechanism in the ABC Transporter BtuCD-F.Molecular insight into conformational transmission of human P-glycoprotein.In silico model for P-glycoprotein substrate prediction: insights from molecular dynamics and in vitro studies.Substrate-induced conformational changes in the nucleotide-binding domains of lipid bilayer-associated P-glycoprotein during ATP hydrolysis.Substrate versus inhibitor dynamics of P-glycoprotein.Allosteric effects of ATP binding on the nucleotide-binding domain of a heterodimeric ATP-binding cassette transporter.Dissecting the Forces that Dominate Dimerization of the Nucleotide Binding Domains of ABCB1.Nucleotide-Induced Conformational Dynamics in ABC Transporters from Structure-Based Coarse Grained Modeling
P2860
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P2860
Opening of the ADP-bound active site in the ABC transporter ATPase dimer: evidence for a constant contact, alternating sites model for the catalytic cycle.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Opening of the ADP-bound activ ...... model for the catalytic cycle.
@en
Opening of the ADP-bound activ ...... model for the catalytic cycle.
@nl
type
label
Opening of the ADP-bound activ ...... model for the catalytic cycle.
@en
Opening of the ADP-bound activ ...... model for the catalytic cycle.
@nl
prefLabel
Opening of the ADP-bound activ ...... model for the catalytic cycle.
@en
Opening of the ADP-bound activ ...... model for the catalytic cycle.
@nl
P356
P1433
P1476
Opening of the ADP-bound activ ...... model for the catalytic cycle
@en
P2093
Peter M Jones
P304
P356
10.1002/PROT.22250
P407
P577
2009-05-01T00:00:00Z