Discovery of new GPCR ligands to illuminate new biology.

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年学术文章

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2017年學術文章

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2017年學術文章

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name

Discovery of new GPCR ligands to illuminate new biology.

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Discovery of new GPCR ligands to illuminate new biology.

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type

Item

label

Discovery of new GPCR ligands to illuminate new biology.

@en

Discovery of new GPCR ligands to illuminate new biology.

@nl

prefLabel

Discovery of new GPCR ligands to illuminate new biology.

@en

Discovery of new GPCR ligands to illuminate new biology.

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P1476

Discovery of new GPCR ligands to illuminate new biology.

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P2093

Brian K Shoichet

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Bryan L Roth

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John J Irwin

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P2860

Functional Selectivity and Classical Concepts of Quantitative Pharmacology

Chemical lead optimization of a pan Gq mAChR M1, M3, M5 positive allosteric modulator (PAM) lead. Part II: development of a potent and highly selective M1 PAM

Crystal structure-based virtual screening for fragment-like ligands of the human histamine H(1) receptor

Structure-based activity prediction for an enzyme of unknown function

Structure-based discovery of opioid analgesics with reduced side effects.

Structure-based discovery of a novel, noncovalent inhibitor of AmpC beta-lactamase

Discovery of 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide (apixaban, BMS-562247), a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulat

Molecular docking and ligand specificity in fragment-based inhibitor discovery

Docking for fragment inhibitors of AmpC -lactamase

Conserved Binding Mode of Human β 2 Adrenergic Receptor Inverse Agonists and Antagonist Revealed by X-ray Crystallography

P2888

nchembio.2490

P304

1143-1151

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P31

scholarly article

P356

10.1038/NCHEMBIO.2490

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P577

2017-10-18T00:00:00Z

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P698

29045379

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P921

G protein-coupled receptor

P932

5835362

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