Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells.
about
Genome engineering of stem cell organoids for disease modeling.Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery.Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool.Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis.Functional interrogation of non-coding DNA through CRISPR genome editing.Progress in Genome Editing Technology and Its Application in Plants.Progress and prospects in plant genome editing.Genome-wide target specificities of CRISPR RNA-guided programmable deaminases.Treatment of Dyslipidemia Using CRISPR/Cas9 Genome Editing.Editing base in mouse model.Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusionsEffective gene editing by high-fidelity base editor 2 in mouse zygotes.Highly efficient base editing in human tripronuclear zygotes.CRISPR-STOP: gene silencing through base-editing-induced nonsense mutations.In Vivo Base Editing of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) as a Therapeutic Alternative to Genome Editing.Immunity to CRISPR Cas9 and Cas12a therapeutics.Genome Editing: The Recent History and Perspective in Cardiovascular Diseases.A Single-Chain Photoswitchable CRISPR-Cas9 Architecture for Light-Inducible Gene Editing and Transcription.Editing the Genome Without Double-Stranded DNA Breaks.CRISPRi and CRISPRa Screens in Mammalian Cells for Precision Biology and Medicine.CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons.Targeted Base Editing via RNA-Guided Cytidine Deaminases in Xenopus laevis Embryos.Am I ready for CRISPR? A user's guide to genetic screens.Modern methods for laboratory diversification of biomolecules.High-Throughput Approaches to Pinpoint Function within the Noncoding Genome.Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes.CRISPR-Cas9 Genome Editing for Treatment of Atherogenic Dyslipidemia.Cas9, Cpf1 and C2c1/2/3-What's next?Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes.CRISPR-Cas9-mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy.Updated summary of genome editing technology in human cultured cells linked to human genetics studies.Harnessing natural DNA modifying activities for editing of the genome and epigenome.Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion.Highly efficient RNA-guided base editing in mouse embryos.A Rice Dual-localized Pentatricopeptide Repeat Protein is involved in Organellar RNA Editing together with OsMORFs.Choosing CRISPR-based screens in cancer.Genome Editing: Past, Present, and Future.Programmable Single and Multiplex Base-Editing in Bombyx mori Using RNA-Guided Cytidine Deaminases.CRISPR base editors: genome editing without double-stranded breaks.
P2860
Q33628093-968D446F-31DB-4416-B2BE-BEB376D85FD3Q33786397-0D270744-70D4-430D-B4FA-1DE6E928F6A3Q36258853-D1F45954-4F6B-45EB-B095-52427F54E6A7Q36288331-A6FAACD7-4948-46B0-AF8A-5F7EE86A8C02Q36306820-A915B5E8-098B-42AC-8A6F-9F6A12858286Q37639765-10832166-654A-43C5-91E5-EDB11B3C6A59Q38649381-D2DC18DA-FDCE-482B-8F3B-9E190A3AADAAQ38842681-2B70889F-2E8F-4471-AA36-F850F05BA76EQ39333650-66934DC9-BDBA-4B94-B26D-550522727125Q41285231-1037C36B-EF72-4E47-9C60-D1E092F59AD5Q41562658-5B78A6E9-7671-480E-9EA9-0171BEDA2273Q41960134-E79393BA-BFED-44E6-AA26-A7B34715C88CQ42343182-4F6B0E8C-52E8-4826-A4C5-6B418B38F289Q42651117-CD843077-EFE7-4C02-B5D2-499A831986C4Q45060692-AC895570-62B1-417A-B000-691BA74CE07EQ45870138-FD141FFB-DAFF-4560-85DF-E2255C37DEEEQ45873745-ABEE36CA-890D-43EC-B8A8-FF11F0AB8E41Q45875285-A429059E-248D-47B7-83DB-A4A1511FBF5BQ45981156-707512D5-529D-4BB9-970A-8BDECF6964B4Q45996655-BE8191DF-BEE7-4F1A-9526-AD4B7B752E2FQ46190066-91FAB6CA-7812-4852-A4E3-693E91728145Q46309410-DD5BA71E-1792-4BCA-ABB9-5E0BC2CAD400Q47128146-9D2C7871-FD26-40DC-ADC3-E8293CA59AA5Q47281660-1DE02C7C-8884-4A4E-BC18-A051A4C4558EQ47387337-E6F54A22-4E83-495A-914D-1369C01D2953Q47594697-E3421FCA-47EB-4453-9534-E7B20DBE47ACQ47594709-C28684E6-EBA0-4909-A86B-49EFBB961C77Q47909228-3F4EF4B7-CDE6-4F75-868D-02B2DCC76B15Q47990831-CFBAC286-B3E7-4933-9C20-B6F36F35C7C9Q48103480-BE0B8701-5FBA-431D-961F-DAB57549E365Q48112768-230B0414-97D2-43D5-910D-D92CC9522D31Q48540221-E92E9429-4D4B-422C-ABD3-6291116A12BEQ49917892-E303252F-CF04-4C83-B1F1-31786E0E5A4DQ50453614-403360C5-4534-4FBB-AC8E-1C9985DBA422Q50986337-D1F3907B-7CD0-4844-9EE8-F5478D0A61DEQ52347620-8CDA8C53-4587-4524-B8A9-9F22BD101234Q52427338-0923231A-E4A7-4675-935C-8348FC5FD6A3Q52429681-032BEE03-C6EB-46D1-B992-B335FE9B30B6Q52430904-DBAE39B2-7E39-42E1-803A-6B8855E9D5B4Q55172646-2BE70A47-D0B0-4A2E-9973-A181B92197E4
P2860
Targeted AID-mediated mutagenesis (TAM) enables efficient genomic diversification in mammalian cells.
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年学术文章
@wuu
2016年学术文章
@zh-cn
2016年学术文章
@zh-hans
2016年学术文章
@zh-my
2016年学术文章
@zh-sg
2016年學術文章
@yue
2016年學術文章
@zh
2016年學術文章
@zh-hant
name
Targeted AID-mediated mutagene ...... sification in mammalian cells.
@en
Targeted AID-mediated mutagenesis
@nl
type
label
Targeted AID-mediated mutagene ...... sification in mammalian cells.
@en
Targeted AID-mediated mutagenesis
@nl
prefLabel
Targeted AID-mediated mutagene ...... sification in mammalian cells.
@en
Targeted AID-mediated mutagenesis
@nl
P2093
P356
P1433
P1476
Targeted AID-mediated mutagene ...... sification in mammalian cells.
@en
P2093
Jiayuan Zhang
Weijie Yin
Yunqing Ma
Zhenchao Zhang
P2888
P304
P356
10.1038/NMETH.4027
P50
P577
2016-10-10T00:00:00Z