Purity-activity relationships of natural products: the case of anti-TB active ursolic acid.
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Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?Countercurrent Separation of Natural Products: An UpdateA cell-free fluorometric high-throughput screen for inhibitors of Rtt109-catalyzed histone acetylationImportance of purity evaluation and the potential of quantitative ¹H NMR as a purity assay.Antibiotics in Canadian poultry productions and anticipated alternativesThe essential roles of chemistry in high-throughput screening triagePAINS in the assay: chemical mechanisms of assay interference and promiscuous enzymatic inhibition observed during a sulfhydryl-scavenging HTS.Using NMR to identify and characterize natural products.Discovery of plant phenolic compounds that act as type III secretion system inhibitors or inducers of the fire blight pathogen, Erwinia amylovora.Potential therapeutic effect of Allium cepa L. and quercetin in a murine model of Blomia tropicalis induced asthma.Analysis and purification of bioactive natural products: the AnaPurNa study.Quantitative 1H NMR. Development and potential of an analytical method: an updateDereplication, residual complexity, and rational naming: the case of the Actaea triterpenesDynamic residual complexity of natural products by qHNMR: solution stability of desmethylxanthohumol.Plant antimicrobial agents and their effects on plant and human pathogensValidation of a generic quantitative (1)H NMR method for natural products analysis.Dereplication: racing to speed up the natural products discovery process.Two new triterpenes from Euphorbia alatavica.A Cytotoxic and Anti-inflammatory Campesterol Derivative from Genetically Transformed Hairy Roots of Lopezia racemosa Cav. (Onagraceae).Orthogonal Analysis Underscores the Relevance of Primary and Secondary Metabolites in Licorice.Antiprotozoal and Antimycobacterial Activities of Pure Compounds from Aristolochia elegans Rhizomes.Antimycobacterial, docking and molecular dynamic studies of pentacyclic triterpenes from Buddleja saligna leaves.Residual Complexity Does Impact Organic Chemistry and Drug Discovery: The Case of Rufomyazine and Rufomycin.Conjugates of several lupane, oleanane, and ursane triterpenoids with the antituberculosis drug isoniazid and pyridinecarboxaldehydes
P2860
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P2860
Purity-activity relationships of natural products: the case of anti-TB active ursolic acid.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Purity-activity relationships ...... f anti-TB active ursolic acid.
@en
Purity-activity relationships ...... f anti-TB active ursolic acid.
@nl
type
label
Purity-activity relationships ...... f anti-TB active ursolic acid.
@en
Purity-activity relationships ...... f anti-TB active ursolic acid.
@nl
prefLabel
Purity-activity relationships ...... f anti-TB active ursolic acid.
@en
Purity-activity relationships ...... f anti-TB active ursolic acid.
@nl
P2093
P356
P1476
Purity-activity relationships ...... f anti-TB active ursolic acid.
@en
P2093
Birgit U Jaki
David C Lankin
Fangqiu Zhang
Lucas R Chadwick
Yuehong Wang
P304
P356
10.1021/NP800329J
P577
2008-09-18T00:00:00Z