USP7 small-molecule inhibitors interfere with ubiquitin binding. - Wikidata - wikimedia - TriplyDB

USP7 small-molecule inhibitors interfere with ubiquitin binding.

USP7 small-molecule inhibitors interfere with ubiquitin binding.

http://www.wikidata.org/entity/Q46429336

about

Current NMR Techniques for Structure-Based Drug Discovery.Discovery and characterization of highly potent and selective allosteric USP7 inhibitors.Drug development: Allosteric inhibitors hit USP7 hard.Targeting HAUSP in both p53 wildtype and p53-mutant tumors.Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.Molecular dynamics simulation reveals the possible druggable of USP7 The MALDI-TOF E2/E3 Ligase Assay as Universal Tool for Drug Discovery in the Ubiquitin Pathway Identification and Characterization of USP7 Targets in Cancer Cells The structure of the deubiquitinase USP15 reveals a misaligned catalytic triad and an open ubiquitin-binding channel USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation Prevalence of MDM2 amplification and coalterations in 523 advanced cancer patients in the MD Anderson phase 1 clinic

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USP7 small-molecule inhibitors interfere with ubiquitin binding.

http://www.wikidata.org/entity/Q46429336

description

2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

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2017年学术文章

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2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

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2017年學術文章

@yue

2017年學術文章

@zh-hant

name

USP7 small-molecule inhibitors interfere with ubiquitin binding.

@en

USP7 small-molecule inhibitors interfere with ubiquitin binding.

@nl

type

label

USP7 small-molecule inhibitors interfere with ubiquitin binding.

@en

USP7 small-molecule inhibitors interfere with ubiquitin binding.

@nl

prefLabel

USP7 small-molecule inhibitors interfere with ubiquitin binding.

@en

USP7 small-molecule inhibitors interfere with ubiquitin binding.

@nl

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USP7 small-molecule inhibitors interfere with ubiquitin binding.

@en

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Adam R Renslo

http://www.w3.org/2001/XMLSchema#string

Bradley Brasher

http://www.w3.org/2001/XMLSchema#string

Brian R Hearn

http://www.w3.org/2001/XMLSchema#string

Carsten Schwerdtfeger

http://www.w3.org/2001/XMLSchema#string

Christiaan Klijn

http://www.w3.org/2001/XMLSchema#string

Dario R Alessi

http://www.w3.org/2001/XMLSchema#string

Elizabeth Blackwood

http://www.w3.org/2001/XMLSchema#string

Eva Lin

http://www.w3.org/2001/XMLSchema#string

Frank Peale

http://www.w3.org/2001/XMLSchema#string

Frederick Cohen

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde

p53 in the DNA-Damage-Repair Process

Medical genetics: a marker for Stevens-Johnson syndrome

The ubiquitin code

USP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental Disorder

Inactivation of HAUSP in vivo modulates p53 function.

Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme.

Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions.

The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes.

Screening of DUB activity and specificity by MALDI-TOF mass spectrometry

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534-538

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scholarly article

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10.1038/NATURE24006

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P433

7677

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550

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Chudi O Ndubaku

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2017-10-18T00:00:00Z

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29045385

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