The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling. - Wikidata - wikimedia - TriplyDB

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.

http://www.wikidata.org/entity/Q46438489

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Regulation of miRNA transcription in macrophages in response to Candida albicans Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases Emerging Roles of the Mitogen and Stress Activated Kinases MSK1 and MSK2 Regulation of IL-10 and IL-12 production and function in macrophages and dendritic cells Mitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage Biology Intracellular nucleic acid sensors and autoimmunity MKP-1: a critical phosphatase in the biology of macrophages controlling the switch between proliferation and activation The TLR and IL-1 signalling network at a glance The Crystal Structure of the Active Form of the C-Terminal Kinase Domain of Mitogen- and Stress-Activated Protein Kinase 1 The role of IL-10 in Mycobacterium avium subsp. paratuberculosis infection Methane limit LPS-induced NF-κB/MAPKs signal in macrophages and suppress immune response in mice by enhancing PI3K/AKT/GSK-3β-mediated IL-10 expression Comprehensive logic based analyses of Toll-like receptor 4 signal transduction pathway The mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumonia Accelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2.Toll-like receptor signaling in cell proliferation and survival Roles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatases Cyclophosphamide induces bone marrow to yield higher numbers of precursor dendritic cells in vitro capable of functional antigen presentation to T cells in vivo.Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.The role of the transcription factor CREB in immune function.Comparison of epigenetic mediator expression and function in mouse and human embryonic blastomeres The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanism The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity.The AGC kinase inhibitor H89 attenuates airway inflammation in mouse models of asthma Kinase drug discovery--what's next in the field?TLR and TNF-R1 activation of the MKK3/MKK6-p38α axis in macrophages is mediated by TPL-2 kinase.Histone code pathway involving H3 S28 phosphorylation and K27 acetylation activates transcription and antagonizes polycomb silencing Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers Safety profile of protein kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis.Mitogen- and stress-activated protein kinases 1 and 2 are required for maximal trefoil factor 1 induction Shigella flexneri targets the HP1γ subcode through the phosphothreonine lyase OspF Transcriptomic and proteomic analyses reveal key innate immune signatures in the host response to the gastrointestinal pathogen Campylobacter concisus Transcription of Tnfaip3 is regulated by NF-κB and p38 via C/EBPβ in activated macrophages.Phosphorylation of mitogen- and stress-activated protein kinase-1 in astrocytic inflammation: a possible role in inhibiting production of inflammatory cytokines.Interleukin-10 and immunity against prokaryotic and eukaryotic intracellular pathogens.Lack of a Functioning P2X7 Receptor Leads to Increased Susceptibility to Toxoplasmic Ileitis.Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genes Mitogen-activated protein kinase phosphatase-1 inhibits myocardial TNF-α expression and improves cardiac function during endotoxemia.IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism.

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The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.

http://www.wikidata.org/entity/Q46438489

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

@yue

2008年學術文章

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name

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.

@en

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.

@nl

type

label

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.

@en

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.

@nl

prefLabel

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.

@en

The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.

@nl

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Nature Immunology

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The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.

@en

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Andrew Wingate

http://www.w3.org/2001/XMLSchema#string

Claire E Monk

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J Simon C Arthur

http://www.w3.org/2001/XMLSchema#string

Jin Mo Park

http://www.w3.org/2001/XMLSchema#string

Joanne Darragh

http://www.w3.org/2001/XMLSchema#string

Julia M Carr

http://www.w3.org/2001/XMLSchema#string

Olga Ananieva

http://www.w3.org/2001/XMLSchema#string

Rachel Toth

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P2860

The enigma of sepsis.

Dynamic and transient remodeling of the macrophage IL-10 promoter during transcription

Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages.

Macrophage deletion of p38alpha partially impairs lipopolysaccharide-induced cellular activation.

Essential role of MAPK phosphatase-1 in the negative control of innate immune responses.

Identification of a macrophage-specific chromatin signature in the IL-10 locus.

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1028-1036

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scholarly article

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10.1038/NI.1644

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P433

9

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9

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Susana G. Santos

Joanne McIlrath

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2008-09-01T00:00:00Z

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23158975

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18690222

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Toll-like receptor