The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
about
Regulation of miRNA transcription in macrophages in response to Candida albicansPhosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophagesActivation and function of the MAPKs and their substrates, the MAPK-activated protein kinasesEmerging Roles of the Mitogen and Stress Activated Kinases MSK1 and MSK2Regulation of IL-10 and IL-12 production and function in macrophages and dendritic cellsMitogen-Activated Protein Kinases and Mitogen Kinase Phosphatase 1: A Critical Interplay in Macrophage BiologyIntracellular nucleic acid sensors and autoimmunityMKP-1: a critical phosphatase in the biology of macrophages controlling the switch between proliferation and activationThe TLR and IL-1 signalling network at a glanceThe Crystal Structure of the Active Form of the C-Terminal Kinase Domain of Mitogen- and Stress-Activated Protein Kinase 1The role of IL-10 in Mycobacterium avium subsp. paratuberculosis infectionMethane limit LPS-induced NF-κB/MAPKs signal in macrophages and suppress immune response in mice by enhancing PI3K/AKT/GSK-3β-mediated IL-10 expressionComprehensive logic based analyses of Toll-like receptor 4 signal transduction pathwayThe mito-DAMP cardiolipin blocks IL-10 production causing persistent inflammation during bacterial pneumoniaAccelerated apoptotic death and in vivo turnover of erythrocytes in mice lacking functional mitogen- and stress-activated kinase MSK1/2.Toll-like receptor signaling in cell proliferation and survivalRoles of the TRAF6 and Pellino E3 ligases in MyD88 and RANKL signaling.Crosstalk in inflammation: the interplay of glucocorticoid receptor-based mechanisms and kinases and phosphatasesCyclophosphamide induces bone marrow to yield higher numbers of precursor dendritic cells in vitro capable of functional antigen presentation to T cells in vivo.Indirect inhibition of Toll-like receptor and type I interferon responses by ITAM-coupled receptors and integrins.The role of the transcription factor CREB in immune function.Comparison of epigenetic mediator expression and function in mouse and human embryonic blastomeresThe p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanismThe pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity.The AGC kinase inhibitor H89 attenuates airway inflammation in mouse models of asthmaKinase drug discovery--what's next in the field?TLR and TNF-R1 activation of the MKK3/MKK6-p38α axis in macrophages is mediated by TPL-2 kinase.Histone code pathway involving H3 S28 phosphorylation and K27 acetylation activates transcription and antagonizes polycomb silencingDectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markersSafety profile of protein kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis.Mitogen- and stress-activated protein kinases 1 and 2 are required for maximal trefoil factor 1 inductionShigella flexneri targets the HP1γ subcode through the phosphothreonine lyase OspFTranscriptomic and proteomic analyses reveal key innate immune signatures in the host response to the gastrointestinal pathogen Campylobacter concisusTranscription of Tnfaip3 is regulated by NF-κB and p38 via C/EBPβ in activated macrophages.Phosphorylation of mitogen- and stress-activated protein kinase-1 in astrocytic inflammation: a possible role in inhibiting production of inflammatory cytokines.Interleukin-10 and immunity against prokaryotic and eukaryotic intracellular pathogens.Lack of a Functioning P2X7 Receptor Leads to Increased Susceptibility to Toxoplasmic Ileitis.Mitogen- and stress-activated kinase 1 (MSK1) regulates cigarette smoke-induced histone modifications on NF-κB-dependent genesMitogen-activated protein kinase phosphatase-1 inhibits myocardial TNF-α expression and improves cardiac function during endotoxemia.IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism.
P2860
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P2860
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
@en
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
@nl
type
label
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
@en
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
@nl
prefLabel
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
@en
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
@nl
P2093
P2860
P50
P356
P1433
P1476
The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling.
@en
P2093
Andrew Wingate
Claire E Monk
J Simon C Arthur
Jin Mo Park
Joanne Darragh
Julia M Carr
Olga Ananieva
Rachel Toth
P2860
P304
P356
10.1038/NI.1644
P407
P577
2008-09-01T00:00:00Z