Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies. - Wikidata - wikimedia - TriplyDB

Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies.

Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies.

http://www.wikidata.org/entity/Q46468372

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The impact of divergence time on the nature of population structure: an example from Iceland Genetic structure of Europeans: a view from the North-East Geographic patterns of genome admixture in Latin American Mestizos Genetic variation and population structure in native Americans Isolated populations and complex disease gene identification High differentiation among eight villages in a secluded area of Sardinia revealed by genome-wide high density SNPs analysis Toward a better understanding of ADHD: LPHN3 gene variants and the susceptibility to develop ADHD Genome-wide association study of Tourette's syndrome Population structure and genome-wide patterns of variation in Ireland and Britain Genetic markers and population history: Finland revisited Replication of association between working memory and Reelin, a potential modifier gene in schizophrenia Signatures of founder effects, admixture, and selection in the Ashkenazi Jewish population Genome-wide association scan for five major dimensions of personality An association analysis of murine anxiety genes in humans implicates novel candidate genes for anxiety disorders Fine mapping on chromosome 10q22-q23 implicates Neuregulin 3 in schizophrenia Genome-wide association analysis of metabolic traits in a birth cohort from a founder population FOXE1 association with both isolated cleft lip with or without cleft palate, and isolated cleft palate Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene Comprehensive testing of positionally cloned asthma genes in two populations Systems biology of the vervet monkey Genome-wide analysis of single nucleotide polymorphisms uncovers population structure in Northern Europe Replication of linkage on chromosome 7q22 and association of the regional Reelin gene with working memory in schizophrenia families A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication Mitogenomic and microsatellite variation in descendants of the founder population of Newfoundland: high genetic diversity in an historically isolated population Interaction of early environment, gender and genes of monoamine neurotransmission in the aetiology of depression in a large population-based Finnish birth cohort The genome-wide patterns of variation expose significant substructure in a founder population Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis Genetics of Type 2 Diabetes: the Power of Isolated Populations.Identification of novel susceptibility loci for Guam neurodegenerative disease: challenges of genome scans in genetic isolates.Association analysis of MAPT H1 haplotype and subhaplotypes in Parkinson's disease.Simulation of Finnish population history, guided by empirical genetic data, to assess power of rare-variant tests in Finland.Analysis of genetic variation in Ashkenazi Jews by high density SNP genotyping.Volume measures for linkage disequilibrium.Combined effects of thrombosis pathway gene variants predict cardiovascular events.The value of some Corsican sub-populations for genetic association studies.Linkage disequilibrium compared between five populations of domestic sheep A role of BRCA1 and BRCA2 germline mutations in breast cancer susceptibility within Sardinian population Decay of linkage disequilibrium within genes across HGDP-CEPH human samples: most population isolates do not show increased LD.Association between protective and deleterious HLA alleles with multiple sclerosis in Central East Sardinia.Systematic analysis of circadian genes in a population-based sample reveals association of TIMELESS with depression and sleep disturbance.

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P2860

Magnitude and distribution of linkage disequilibrium in population isolates and implications for genome-wide association studies.

http://www.wikidata.org/entity/Q46468372

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Andres Ruiz-Linares

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António Macedo

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Ben Oostra

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Chiara Sabatti

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Gabriel Bedoya

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Herman Pretorious

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J Louw Roos

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Jorge Ospina

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Joseph DeYoung

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Luana Galver

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P2860

High-resolution whole-genome association study of Parkinson disease.

Linkage disequilibrium in humans: models and data.

The linkage disequilibrium maps of three human chromosomes across four populations reflect their demographic history and a common underlying recombination pattern.

Population choice in mapping genes for complex diseases.

Extended intermarker linkage disequilibrium in the Afrikaners.

A combined linkage-physical map of the human genome

The first linkage disequilibrium (LD) maps: delineation of hot and cold blocks by diplotype analysis.

Recent developments in genomewide association scans: a workshop summary and review

Use of population isolates for mapping complex traits.

The fine-scale structure of recombination rate variation in the human genome.

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10.1038/NG1770

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Leena Peltonen-Palotie

Marjo-Riitta Järvelin

Cornelia M. van Duijn

Yurii S. Aulchenko

Joana Almeida Palha

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genome-wide association study