Modeling the MHC class I pathway by combining predictions of proteasomal cleavage, TAP transport and MHC class I binding.
about
A peptide filtering relation quantifies MHC class I peptide optimizationFrom functional genomics to functional immunomics: new challenges, old problems, big rewardsImmunoinformatics comes of ageGenerating quantitative models describing the sequence specificity of biological processes with the stabilized matrix method.Mechanisms of HIV protein degradation into epitopes: implications for vaccine designDrug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoireNetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequenceAcyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity.ImmunoNodes - graphical development of complex immunoinformatics workflowsMHC class II epitope predictive algorithms.Unconventional Peptide Presentation by Major Histocompatibility Complex (MHC) Class I Allele HLA-A*02:01: BREAKING CONFINEMENT.The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine DesignThe contributions of mass spectrometry to understanding of immune recognition by T lymphocytes.Computational prediction of cleavage using proteasomal in vitro digestion and MHC I ligand data.In silico-based vaccine design against Ebola virus glycoproteinEpiJen: a server for multistep T cell epitope prediction.A community resource benchmarking predictions of peptide binding to MHC-I molecules.Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction.HLA class I supertypes: a revised and updated classification.Quantitative peptide binding motifs for 19 human and mouse MHC class I molecules derived using positional scanning combinatorial peptide libraries.Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes.The specificity and polymorphism of the MHC class I prevents the global adaptation of HIV-1 to the monomorphic proteasome and TAP.The distribution of CTL epitopes in HIV-1 appears to be random, and similar to that of other proteomes.The 20S proteasome splicing activity discovered by SpliceMet.High throughput T epitope mapping and vaccine developmentComputational analysis and modeling of cleavage by the immunoproteasome and the constitutive proteasomeThe specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum.NetCTLpan: pan-specific MHC class I pathway epitope predictionsIntra- and inter-clade cross-reactivity by HIV-1 Gag specific T-cells reveals exclusive and commonly targeted regions: implications for current vaccine trialsDendritic cells restore CD8+ T cell reactivity to autologous HIV-1POPISK: T-cell reactivity prediction using support vector machines and string kernels.Computer aided prediction and identification of potential epitopes in the receptor binding domain (RBD) of spike (S) glycoprotein of MERS-CoV.Proteome sampling by the HLA class I antigen processing pathwayState of the art and challenges in sequence based T-cell epitope predictionCD8 T cell epitope distribution in viruses reveals patterns of protein biosynthesis.Applications for T-cell epitope queries and tools in the Immune Epitope Database and Analysis Resource.Proteasomes shape the repertoire of T cells participating in antigen-specific immune responses.PRED(TAP): a system for prediction of peptide binding to the human transporter associated with antigen processing.Potential elucidation of a novel CTL epitope in HIV-1 protease by the protease inhibitor resistance mutation L90M.Identification of protective Lassa virus epitopes that are restricted by HLA-A2.
P2860
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P2860
Modeling the MHC class I pathway by combining predictions of proteasomal cleavage, TAP transport and MHC class I binding.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Modeling the MHC class I pathw ...... sport and MHC class I binding.
@en
Modeling the MHC class I pathw ...... sport and MHC class I binding.
@nl
type
label
Modeling the MHC class I pathw ...... sport and MHC class I binding.
@en
Modeling the MHC class I pathw ...... sport and MHC class I binding.
@nl
prefLabel
Modeling the MHC class I pathw ...... sport and MHC class I binding.
@en
Modeling the MHC class I pathw ...... sport and MHC class I binding.
@nl
P2093
P1476
Modeling the MHC class I pathw ...... sport and MHC class I binding.
@en
P2093
H-G Holzhütter
H-G Rammensee
M M Schatz
P-M Kloetzel
P2888
P304
P356
10.1007/S00018-005-4528-2
P577
2005-05-01T00:00:00Z