Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation.
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Optimization of time-course experiments for kinetic model discriminationOrganogenic nodule development in hop (Humulus lupulus L.): transcript and metabolic responses.Specificity of the trypanothione-dependent Leishmania major glyoxalase I: structure and biochemical comparison with the human enzyme.Glycobiology of the Leishmania parasite and emerging targets for antileishmanial drug discovery.Methylglyoxal metabolism in trypanosomes and leishmania.Glyoxalase diversity in parasitic protists.In-silico Leishmania target selectivity of antiparasitic terpenoids.Purification, crystallization and preliminary X-ray diffraction analysis of the glyoxalase II from Leishmania infantum.Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of glyoxalase I from Leishmania infantum.Characterization of the gene encoding glyoxalase II from Leishmania donovani: a potential target for anti-parasite drugsATP-dependent ligases in trypanothione biosynthesis--kinetics of catalysis and inhibition by phosphinic acid pseudopeptides.Plasmodium falciparum glyoxalase II: Theorell-Chance product inhibition patterns, rate-limiting substrate binding via Arg(257)/Lys(260), and unmasking of acid-base catalysis.Drug target validation of the trypanothione pathway enzymes through metabolic modelling.
P2860
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P2860
Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
@zh-hans
2005年学术文章
@zh-my
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@yue
2005年學術文章
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name
Quantitative assessment of the ...... lling and computer simulation.
@en
Quantitative assessment of the ...... lling and computer simulation.
@nl
type
label
Quantitative assessment of the ...... lling and computer simulation.
@en
Quantitative assessment of the ...... lling and computer simulation.
@nl
prefLabel
Quantitative assessment of the ...... lling and computer simulation.
@en
Quantitative assessment of the ...... lling and computer simulation.
@nl
P2093
P50
P1433
P1476
Quantitative assessment of the ...... elling and computer simulation
@en
P2093
Ana Maria Tomás
Ana Ponces Freire
António E N Ferreira
Marta Sousa Silva
P2860
P304
P356
10.1111/J.1742-4658.2005.04632.X
P407
P577
2005-05-01T00:00:00Z