Metabolic challenge to glia activates an adenosine-mediated safety mechanism that promotes neuronal survival by delaying the onset of spreading depression waves.
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Spreading Depression, Spreading Depolarizations, and the Cerebral VasculatureThe antiepileptic drug levetiracetam suppresses non-convulsive seizure activity and reduces ischemic brain damage in rats subjected to permanent middle cerebral artery occlusionAdenosine and inosine release during hypoxia in the isolated spinal cord of neonatal ratsNicotine uses neuron-glia communication to enhance hippocampal synaptic transmission and long-term memory.The role of astrocyte mitochondria in differential regional susceptibility to environmental neurotoxicants: tools for understanding neurodegenerationSpreading convulsions, spreading depolarization and epileptogenesis in human cerebral cortexPersistent astroglial swelling accompanies rapid reversible dendritic injury during stroke-induced spreading depolarizations.Adenosine receptor activation is responsible for prolonged depression of synaptic transmission after spreading depolarization in brain slicesMultifaceted roles for astrocytes in spreading depolarization: A target for limiting spreading depolarization in acute brain injury?Peri-infarct blood-brain barrier dysfunction facilitates induction of spreading depolarization associated with epileptiform discharges.Direct measurement of oxidative metabolism in the living brain by microdialysis: a review.Ciliary neurotrophic factor (CNTF) activation of astrocytes decreases spreading depolarization susceptibility and increases potassium clearance.Release of adenosine and ATP during ischemia and epilepsy.Adenosine receptors and epilepsy: current evidence and future potential.Mechanisms of spreading depolarization in vertebrate and insect central nervous systemsHow does adenosine control neuronal dysfunction and neurodegeneration?Pharmacological Tools to Study the Role of Astrocytes in Neural Network Functions.Contribution of astrocyte glycogen stores to progression of spreading depression and related events in hippocampal slices.K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study.Spreading depolarization-induced adenosine accumulation reflects metabolic status in vitro and in vivo.Cortical spreading depression shifts cell fate determination of progenitor cells in the adult cortex.The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy.Adenosine production by brain cells.Evidence that adenosine contributes to Leao's spreading depression in vivo.Prolonged Dysfunction of Astrocytes and Activation of Microglia Accelerate Degeneration of Dopaminergic Neurons in the Rat Substantia Nigra and Block Compensation of Early Motor Dysfunction Induced by 6-OHDA.Astrocytes restrict discharge duration and neuronal sodium loads during recurrent network activity.Multiple pathways for elevating extracellular adenosine in the rat hippocampal CA1 region characterized by adenosine sensor cells.Chronic daily cortical spreading depressions suppress spreading depression susceptibility.Neuronal transporter and astrocytic ATP exocytosis underlie activity-dependent adenosine release in the hippocampus.The Selective Antagonism of Adenosine A2B Receptors Reduces the Synaptic Failure and Neuronal Death Induced by Oxygen and Glucose Deprivation in Rat CA1 Hippocampus in Vitro.Spreading depolarization, a pathophysiological mechanism of stroke and migraine aura
P2860
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P2860
Metabolic challenge to glia activates an adenosine-mediated safety mechanism that promotes neuronal survival by delaying the onset of spreading depression waves.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Metabolic challenge to glia ac ...... of spreading depression waves.
@en
Metabolic challenge to glia ac ...... of spreading depression waves.
@nl
type
label
Metabolic challenge to glia ac ...... of spreading depression waves.
@en
Metabolic challenge to glia ac ...... of spreading depression waves.
@nl
prefLabel
Metabolic challenge to glia ac ...... of spreading depression waves.
@en
Metabolic challenge to glia ac ...... of spreading depression waves.
@nl
P2093
P2860
P356
P1476
Metabolic challenge to glia ac ...... of spreading depression waves.
@en
P2093
Belén Larrosa
Jesús Pintor
María A Mena
Oscar Herreras
P2860
P304
P356
10.1038/JCBFM.2008.71
P577
2008-07-09T00:00:00Z