Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?
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Why the NIH Trial to Assess Chelation Therapy (TACT) should be abandonedOxidative stress and the use of antioxidants in diabetes: linking basic science to clinical practice.Macrophages in vascular inflammation--From atherosclerosis to vasculitisArginase as a Critical Prooxidant Mediator in the Binomial Endothelial Dysfunction-AtherosclerosisAtherogenesis in perspective: hypercholesterolemia and inflammation as partners in crimeVascular biology of eicosanoids and atherogenesisThematic review series: the pathogenesis of atherosclerosis: an interpretive history of the cholesterol controversy, part III: mechanistically defining the role of hyperlipidemiaAssessment of endothelial dysfunction in childhood obesity and clinical use.Postnatal exposure to voluntary exercise but not the antioxidant catechin protects the vasculature after a switch to an atherogenic environment in middle-age micePhysical training and metabolic supplementation reduce spontaneous atherosclerotic plaque rupture and prolong survival in hypercholesterolemic mice.Divergent effects of alpha-tocopherol and vitamin C on the generation of dysfunctional HDL associated with diabetes and the Hp 2-2 genotype.Alpha-tocopherol is ineffective in preventing the decomposition of preformed lipid peroxides and may promote the accumulation of toxic aldehydes: a potential explanation for the failure of antioxidants to affect human atherosclerosis.Sphingomyelinases: their regulation and roles in cardiovascular pathophysiology.The effect of vitamin E supplementation on cardiovascular risk in diabetic individuals with different haptoglobin phenotypes.Identifying novel genes for atherosclerosis through mouse-human comparative genetics.Genetic reduction of lipoic acid synthase expression modestly increases atherosclerosis in male, but not in female, apolipoprotein E-deficient mice.LOX-1 in atherosclerosis: biological functions and pharmacological modifiers.Bioavailability and antioxidant effects of olive oil phenols in humans: a review.Beneficial effects of antioxidants and L-arginine on oxidation-sensitive gene expression and endothelial NO synthase activity at sites of disturbed shear stress.Lysosomal acid lipase: at the crossroads of normal and atherogenic cholesterol metabolismLong-term combined beneficial effects of physical training and metabolic treatment on atherosclerosis in hypercholesterolemic miceVitamin C supplementation lowers urinary levels of 4-hydroperoxy-2-nonenal metabolites in humansProtective effects of gelam honey against oxidative damage in young and aged ratsThe macrophage foam cell as a target for therapeutic intervention.The Oxidative State of LDL is the Major Determinant of Anti/Prooxidant Effect of Coffee on Cu Catalysed Peroxidation.Haptoglobin 2-2 genotype is not associated with cardiovascular risk in subjects with elevated glycohemoglobin-results from the Bruneck StudyMeasuring reactive species and oxidative damage in vivo and in cell culture: how should you do it and what do the results mean?Simultaneous quantification and inhibitory effect on LDL oxidation of the traditional Korean medicine, Leejung-tang.Dietary compliance, dietary supplementation and traditional remedy usage of type 2 diabetic patients with and without cardiovascular disease.Mechanisms of oxidative stress and vascular dysfunction.Antioxidant vitamin intake and mortality: the Leisure World Cohort Study.Oxidative Stress and Inflammation in Heart Disease: Do Antioxidants Have a Role in Treatment and/or Prevention?Should antioxidant status be considered in interventional trials with antioxidants?Pulsatile versus oscillatory shear stress regulates NADPH oxidase subunit expression: implication for native LDL oxidationPro-oxidant effect of alpha-tocopherol in patients with type 2 diabetes after an oral glucose tolerance test--a randomised controlled trial.Respiration and substrate transport rates as well as reactive oxygen species production distinguish mitochondria from brain and liver.Oxidative stress, antioxidants, and vascular damage.Socioeconomic position and inflammatory and immune biomarkers of cardiovascular disease: applications to the Panel Study of Income Dynamics.Plasma Ascorbic Acid, A Priori Diet Quality Score, and Incident Hypertension: A Prospective Cohort Study.Systemic elevations of free radical oxidation products of arachidonic acid are associated with angiographic evidence of coronary artery disease.
P2860
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P2860
Is the oxidative modification hypothesis relevant to human atherosclerosis? Do the antioxidant trials conducted to date refute the hypothesis?
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh-hant
name
Is the oxidative modification ...... to date refute the hypothesis?
@en
Is the oxidative modification ...... to date refute the hypothesis?
@nl
type
label
Is the oxidative modification ...... to date refute the hypothesis?
@en
Is the oxidative modification ...... to date refute the hypothesis?
@nl
prefLabel
Is the oxidative modification ...... to date refute the hypothesis?
@en
Is the oxidative modification ...... to date refute the hypothesis?
@nl
P1433
P1476
Is the oxidative modification ...... to date refute the hypothesis?
@en
P2093
Daniel Steinberg
P304
P356
10.1161/01.CIR.0000014762.06201.06
P407
P577
2002-04-01T00:00:00Z