The crystal structure of the plexin-semaphorin-integrin domain/hybrid domain/I-EGF1 segment from the human integrin beta2 subunit at 1.8-A resolution.
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A structural hypothesis for the transition between bent and extended conformations of the leukocyte beta2 integrinsStructure of an integrin with an αI domain, complement receptor type 4Structural basis of integrin regulation and signalingAn unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.Integrin conformational regulation: uncoupling extension/tail separation from changes in the head region by a multiresolution approach.Identification of multiple integrin beta1 homologs in zebrafish (Danio rerio)The wild boar (Sus scrofa) lymphocyte function-associated antigen-1 (CD11a/CD18) receptor: cDNA sequencing, structure analysis and comparison with homologuesStructural and mechanical functions of integrins.Effects of limiting extension at the alphaIIb genu on ligand binding to integrin alphaIIbbeta3.Transmembrane and cytoplasmic domains in integrin activation and protein-protein interactions (review).Metal ion and ligand binding of integrin α5β1Identification of integrin beta subunit mutations that alter affinity for extracellular matrix ligand.Regulation of integrin affinity on cell surfacesMapping early conformational changes in alphaIIb and beta3 during biogenesis reveals a potential mechanism for alphaIIbbeta3 adopting its bent conformation.Integrin structures and conformational signalingThree-Dimensional Structures of Full-Length, Membrane-Embedded Human α(IIb)β(3) Integrin ComplexesLeukocyte integrin αLβ2 headpiece structures: The αI domain, the pocket for the internal ligand, and concerted movements of its loops.Integrin structure, activation, and interactionsThe leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.Plexin structures are coming: opportunities for multilevel investigations of semaphorin guidance receptors, their cell signaling mechanisms, and functions.Redox-relevant aspects of the extracellular matrix and its cellular contacts via integrinsRedox regulation of the actin cytoskeleton and its role in the vascular system.Molecular profiling of the "plexinome" in melanoma and pancreatic cancer.The novel S527F mutation in the integrin beta3 chain induces a high affinity alphaIIbbeta3 receptor by hindering adoption of the bent conformation.
P2860
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P2860
The crystal structure of the plexin-semaphorin-integrin domain/hybrid domain/I-EGF1 segment from the human integrin beta2 subunit at 1.8-A resolution.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
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2005年學術文章
@yue
2005年學術文章
@zh-hant
name
The crystal structure of the p ...... 2 subunit at 1.8-A resolution.
@en
The crystal structure of the p ...... 2 subunit at 1.8-A resolution.
@nl
type
label
The crystal structure of the p ...... 2 subunit at 1.8-A resolution.
@en
The crystal structure of the p ...... 2 subunit at 1.8-A resolution.
@nl
prefLabel
The crystal structure of the p ...... 2 subunit at 1.8-A resolution.
@en
The crystal structure of the p ...... 2 subunit at 1.8-A resolution.
@nl
P2093
P2860
P356
P1476
The crystal structure of the p ...... a2 subunit at 1.8-A resolution
@en
P2093
Julien Lescar
Kumar Sundramurthy
MinLong Shi
S K Alex Law
Suet-Mien Tan
P2860
P304
30586-30593
P356
10.1074/JBC.M502525200
P407
P50
P577
2005-06-17T00:00:00Z