A novel GC-rich human macrosatellite VNTR in Xq24 is differentially methylated on active and inactive X chromosomes.
about
The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylationCell cycle-dependent localization of macroH2A in chromatin of the inactive X chromosomeNormal histone modifications on the inactive X chromosome in ICF and Rett syndrome cells: implications for methyl-CpG binding proteinsThe "lnc" between 3D chromatin structure and X chromosome inactivationInfluence of Repressive Histone and DNA Methylation upon D4Z4 Transcription in Non-Myogenic CellsAnalysis of the largest tandemly repeated DNA families in the human genome.Polycomb repressive complex 1 provides a molecular explanation for repeat copy number dependency in FSHD muscular dystrophy.A novel tRNA variable number tandem repeat at human chromosome 1q23.3 is implicated as a boundary element based on conservation of a CTCF motif in mouse.Structural organization of the inactive X chromosome in the mouse.Expression, tandem repeat copy number variation and stability of four macrosatellite arrays in the human genome.DNA replication timing is maintained genome-wide in primary human myoblasts independent of D4Z4 contraction in FSH muscular dystrophySmall RNA expression from the human macrosatellite DXZ4.Variation in array size, monomer composition and expression of the macrosatellite DXZ4Diminishing return for increased Mappability with longer sequencing reads: implications of the k-mer distributions in the human genomeCharacterization of DXZ4 conservation in primates implies important functional roles for CTCF binding, array expression and tandem repeat organization on the X chromosome.YY1 associates with the macrosatellite DXZ4 on the inactive X chromosome and binds with CTCF to a hypomethylated form in some male carcinomas.The macrosatellite DXZ4 mediates CTCF-dependent long-range intrachromosomal interactions on the human inactive X chromosome.A repetitive elements perspective in Polycomb epigenetics.Two novel DXZ4-associated long noncoding RNAs show developmental changes in expression coincident with heterochromatin formation at the human (Homo sapiens) macrosatellite repeatThe mouse DXZ4 homolog retains Ctcf binding and proximity to Pls3 despite substantial organizational differences compared to the primate macrosatellite.DXZ4 chromatin adopts an opposing conformation to that of the surrounding chromosome and acquires a novel inactive X-specific role involving CTCF and antisense transcripts.Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture.X chromosome inactivation: heterogeneity of heterochromatin.Inactive X chromosome-specific reduction in placental DNA methylation.The cell biology of disease: FSHD: copy number variations on the theme of muscular dystrophyEmerging roles of macrosatellite repeats in genome organization and disease development.Structural aspects of the inactive X chromosomeA region of euchromatin coincides with an extensive tandem repeat on the mouse (Mus musculus) inactive X chromosome.A novel molecular mechanism in human genetic disease: a DNA repeat-derived lncRNA.Orientation-dependent Dxz4 contacts shape the 3D structure of the inactive X chromosome.Characterization of the ICCE Repeat in Mammals Reveals an Evolutionary Relationship with the DXZ4 Macrosatellite through Conserved CTCF Binding Motifs
P2860
Q22000593-82AF75EA-E205-45DA-9FFB-F7A3FE9A74F2Q24672610-174F66E8-8ACF-4002-907F-A86BE1CE8A97Q24798816-C612DEA7-2D96-4040-A23B-B934E82DBB85Q26750498-D02ED987-30D4-4225-A8A8-00CDCC5D63A5Q28553207-8D79EC15-EBED-4020-986B-8754CE64DF94Q30851540-28190532-87B1-4A26-8EE7-4622409AAEB2Q33614782-629A7209-6DB0-410D-A6ED-654955A6C293Q33698629-1B6158CF-D660-4C46-ACF5-B9F3D06A9615Q33725284-A0E0E0D9-F17A-44A4-BD61-F094EDA46A1BQ33747006-B31F4432-0181-4500-9601-B9286ED8A31FQ34077893-5975E374-A49F-47C4-9FB2-FF235FAB6981Q34352101-A5BBDD94-5105-43B4-B901-76F8EC8FA1B6Q34841518-907F30DD-1A57-4F96-BD3C-0B5E48865414Q35081386-6A648D5C-F9CF-4DE8-B936-5E8EE5A7D2A8Q35557766-E9C0DD4A-1087-4E11-8F71-8E43483945B6Q35780188-6F08B680-6530-47E1-B239-061151218A9FQ36283345-959A25B0-DF47-4686-9272-E2E6791F621BQ36302696-5CA91E4D-20CC-4588-AA25-0D22DFB46B29Q36342867-04FC3417-1EC6-4250-A186-54772D05AACEQ36377983-0B65AE00-89C5-42D5-9CD8-B386CBE9A6FFQ36804865-44E20F47-96BE-430A-A7A4-AF130258BFA3Q37161595-5B696E7D-72C9-4EA4-8C44-D1E4E780FE00Q37299282-116593DA-565F-4DC3-9A5C-A2ECF3DE9AD0Q37342948-347D9F0C-8078-4B25-A014-595AB0AFF66BQ37819663-3AE2D1BC-7D65-4FE7-A167-35ABB2D97249Q39252070-06FD6A0B-B36F-441D-80B4-9652B4A3A3C5Q42053143-68F64CBD-8BE9-4177-98E2-0BAB011EE455Q42802826-AC509415-1593-4C1F-8E96-2CBB1165C070Q43238618-0E04C7D8-D757-44F6-95CD-BBAC8AA9ADC8Q54942580-4F0E4044-4D3A-4B9B-A7AC-B6DA84E2A239Q58794966-2C80467A-6293-4339-B9F4-E9B02BA46FFE
P2860
A novel GC-rich human macrosatellite VNTR in Xq24 is differentially methylated on active and inactive X chromosomes.
description
1992 nî lūn-bûn
@nan
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
1992年學術文章
@zh-hant
name
A novel GC-rich human macrosat ...... ve and inactive X chromosomes.
@en
A novel GC-rich human macrosat ...... ve and inactive X chromosomes.
@nl
type
label
A novel GC-rich human macrosat ...... ve and inactive X chromosomes.
@en
A novel GC-rich human macrosat ...... ve and inactive X chromosomes.
@nl
prefLabel
A novel GC-rich human macrosat ...... ve and inactive X chromosomes.
@en
A novel GC-rich human macrosat ...... ve and inactive X chromosomes.
@nl
P2093
P2860
P356
P1433
P1476
A novel GC-rich human macrosat ...... ve and inactive X chromosomes.
@en
P2093
P2860
P2888
P304
P356
10.1038/NG0592-137
P407
P577
1992-05-01T00:00:00Z