A robustness screen for the rapid assessment of chemical reactions.
about
Evaluating New Chemistry to Drive Molecular Discovery: Fit for Purpose?Designer substrate library for quantitative, predictive modeling of reaction performanceVirtually instantaneous, room-temperature [(11)C]-cyanation using biaryl phosphine Pd(0) complexesMulticomponent Diene-Transmissive Diels-Alder Sequences Featuring Aminodendralenes.Non-Directed Allylic C-H Acetoxylation in the Presence of Lewis Basic Heterocycles.A unified lead-oriented synthesis of over fifty molecular scaffolds.Highly functionalized biaryls via Suzuki-Miyaura cross-coupling catalyzed by Pd@MOF under batch and continuous flow regimes.Enzyme immunoassays as screening tools for catalysts and reaction discovery.Coordinating activation strategy for C(sp(3))-H/C(sp(3))-H cross-coupling to access β-aromatic α-amino acidsSite-Selective Acylations with Tailor-Made Catalysts.An improved catalyst system for the Pd-catalyzed fluorination of (hetero)aryl triflates.Synthesis of 11C-labeled Sulfonyl Carbamates through a Multicomponent Reaction Employing Sulfonyl Azides, Alcohols, and [11C]CO.Contemporary screening approaches to reaction discovery and development.Catalytic asymmetric desymmetrization approaches to enantioenriched cyclopentanes.Oxidative Coupling of Aryl Boron Reagents with sp(3)-Carbon Nucleophiles: The Enolate Chan-Evans-Lam Reaction.Dual Hypervalent Iodine(III) Reagents and Photoredox Catalysis Enable Decarboxylative Ynonylation under Mild Conditions.Modelling Chemical Reasoning to Predict and Invent Reactions.Transfer of Electrophilic NH Using Convenient Sources of Ammonia: Direct Synthesis of NH Sulfoximines from Sulfoxides.Cu/Mn bimetallic catalysis enables carbonylative Suzuki-Miyaura coupling with unactivated alkyl electrophilesCobalt-catalysed site-selective intra- and intermolecular dehydrogenative amination of unactivated sp(3) carbons.Chemistry informer libraries: a chemoinformatics enabled approach to evaluate and advance synthetic methods.Ruthenium(II)-catalysed remote C-H alkylations as a versatile platform to meta-decorated arenesPractical High-Throughput Experimentation for ChemistsBCl3 -Induced Annulative Oxo- and Thioboration for the Formation of C3-Borylated Benzofurans and Benzothiophenes.Copper-Catalyzed Decarboxylative Trifluoromethylation of Propargyl Bromodifluoroacetates.Combining organometallic reagents, the sulfur dioxide surrogate DABSO, and amines: a one-pot preparation of sulfonamides, amenable to array synthesis.Application of a robustness screen for the evaluation of synthetic organic methodology.Transition-Metal-Free Decarboxylative Iodination: New Routes for Decarboxylative Oxidative Cross-Couplings.Construction of Quaternary Stereocenters by Nickel-Catalyzed Heck Cyclization Reactions.A general, modular method for the catalytic asymmetric synthesis of alkylboronate esters.Pd/C as a catalyst for completely regioselective C-H functionalization of thiophenes under mild conditions.Reaction methodology: Speed dating for reactions.Combining the catalytic enantioselective reaction of visible-light-generated radicals with a by-product utilization system.Diverse bimetallic mechanisms emerging from transition metal Lewis acid/base pairs: development of co-catalysis with metal carbenes and metal carbonyl anions.Diverse Visible-Light-Promoted Functionalizations of Benzotriazoles Inspired by Mechanism-Based Luminescence Screening.Cobalt-Catalyzed C-H Thiolation through Dehydrogenative Cross-Coupling.Electrochemical Synthesis of Aryl Iodides by Anodic Iododesilylation.Manganese(I)-Catalyzed C-H (2-Indolyl)methylation: Expedient Access to Diheteroarylmethanes.Redox-Neutral Manganese(I)-Catalyzed C-H Activation: Traceless Directing Group Enabled Regioselective Annulation.Ligands with 1,10-phenanthroline scaffold for highly regioselective iron-catalyzed alkene hydrosilylation.
P2860
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P2860
A robustness screen for the rapid assessment of chemical reactions.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
A robustness screen for the rapid assessment of chemical reactions.
@en
A robustness screen for the rapid assessment of chemical reactions.
@nl
type
label
A robustness screen for the rapid assessment of chemical reactions.
@en
A robustness screen for the rapid assessment of chemical reactions.
@nl
prefLabel
A robustness screen for the rapid assessment of chemical reactions.
@en
A robustness screen for the rapid assessment of chemical reactions.
@nl
P356
P1433
P1476
A robustness screen for the rapid assessment of chemical reactions.
@en
P2093
Karl D Collins
P2888
P304
P356
10.1038/NCHEM.1669
P577
2013-06-09T00:00:00Z