Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand.
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Translocator protein 18 kDa (TSPO): molecular sensor of brain injury and repairSynthesis and characterization of an MRI Gd-based probe designed to target the translocator protein.Microwave-assisted Organic Synthesis of a High-affinity Pyrazolo-pyrimidinyl TSPO Ligand.Neuroprotective effect of salvianolate lyophilized injection against cerebral ischemia in type 1 diabetic ratsPromising potential of new generation translocator protein tracers providing enhanced contrast of arthritis imaging by positron emission tomography in a rat model of arthritisInitial evaluation of 11C-DPA-713, a novel TSPO PET ligand, in humans.PET imaging of stroke-induced neuroinflammation in mice using [18F]PBR06Synthesis and testing of a p-H2 hyperpolarized 13C probe based on the pyrazolo[1,5-a]pyrimidineacetamide DPA-713, an MRI vector to target the peripheral benzodiazepine receptors.The relationship between serial [(18) F]PBR06 PET imaging of microglial activation and motor function following stroke in mice.Synthesis and structure-activity relationships of 5,6,7-substituted pyrazolopyrimidines: discovery of a novel TSPO PET ligand for cancer imaging.Radiation dosimetry and biodistribution of the TSPO ligand 11C-DPA-713 in humansThe peripheral benzodiazepine receptor (Translocator protein 18kDa) in microglia: from pathology to imaging.Radiosynthesis and in vivo evaluation of two imidazopyridineacetamides, [(11)C]CB184 and [ (11)C]CB190, as a PET tracer for 18 kDa translocator protein: direct comparison with [ (11)C](R)-PK11195.Positron emission tomography imaging of neuroinflammation.Imaging microglial activation during neuroinflammation and Alzheimer's disease.Synthesis of [(125)I]iodoDPA-713: a new probe for imaging inflammation.A molecular imaging primer: modalities, imaging agents, and applications.The potential of carbon-11 and fluorine-18 chemistry: illustration through the development of positron emission tomography radioligands targeting the translocator protein 18 kDa.The translocator protein as a drug target in Alzheimer's disease.Synthesis and cellular uptake of boron-rich pyrazolopyrimidines: exploitation of the translocator protein for the efficient delivery of boron into human glioma cells.New structure-activity relationships of N-acetamide substituted pyrazolopyrimidines as pharmacological ligands of TSPO.Radiosynthesis and Preclinical Evaluation of [18F]F-DPA, A Novel Pyrazolo[1,5a]pyrimidine Acetamide TSPO Radioligand, in Healthy Sprague Dawley Rats[11C]-DPA-713 and [18F]-DPA-714 as new PET tracers for TSPO: a comparison with [11C]-(R)-PK11195 in a rat model of herpes encephalitisKinetic analysis and test-retest variability of the radioligand [11C](R)-PK11195 binding to TSPO in the human brain - a PET study in control subjects.The development of an automated and GMP compliant FASTlab™ Synthesis of [(18) F]GE-180; a radiotracer for imaging translocator protein (TSPO).Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging in Neurological Diseases.(11)C-DPA-713 has much greater specific binding to translocator protein 18 kDa (TSPO) in human brain than (11)C-( R)-PK11195.Imaging Macrophage-associated Inflammation.
P2860
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P2860
Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh-hant
name
Synthesis and in vivo evaluati ...... pine receptor PET radioligand.
@en
Synthesis and in vivo evaluati ...... pine receptor PET radioligand.
@nl
type
label
Synthesis and in vivo evaluati ...... pine receptor PET radioligand.
@en
Synthesis and in vivo evaluati ...... pine receptor PET radioligand.
@nl
prefLabel
Synthesis and in vivo evaluati ...... pine receptor PET radioligand.
@en
Synthesis and in vivo evaluati ...... pine receptor PET radioligand.
@nl
P2093
P1476
Synthesis and in vivo evaluati ...... pine receptor PET radioligand.
@en
P2093
David J Henderson
Frederic Dolle
Michael J Fulham
Michael Kassiou
Michelle L James
Robin D Allan
Roger R Fulton
Sally Thomson
Stefan Eberl
Steven R Meikle
P304
P356
10.1016/J.BMC.2005.06.030
P407
P577
2005-07-20T00:00:00Z