Sortilin and SorLA display distinct roles in processing and trafficking of amyloid precursor protein.
about
Genes associated with Alzheimer's disease: an overview and current statusRole of the Retromer Complex in Neurodegenerative DiseasesAbeta, oxidative stress in Alzheimer disease: evidence based on proteomics studiesA Genetic Variant of the Sortilin 1 Gene is Associated with Reduced Risk of Alzheimer's DiseaseSorCS2-mediated NR2A trafficking regulates motor deficits in Huntington's diseaseThe Intersection of NGF/TrkA Signaling and Amyloid Precursor Protein Processing in Alzheimer's Disease NeuropathologySerum cholesterol and variant in cholesterol-related gene CETP predict white matter microstructureAPP as a Protective Factor in Acute Neuronal Insults.More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegenerationSoluble alpha-APP (sAPPalpha) regulates CDK5 expression and activity in neurons.An exploratory study of the association between SORL1 polymorphisms and sporadic Alzheimer's disease in the Han Chinese population.Spatiotemporal patterns of sortilin and SorCS2 localization during organ development.SORT1 Mutation Resulting in Sortilin Deficiency and p75(NTR) Upregulation in a Family With Essential Tremor.SORL1 mutations in early- and late-onset Alzheimer disease.Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents.Biomarker modelling of early molecular changes in Alzheimer's disease.The dark sides of amyloid in Alzheimer's disease pathogenesis.Pro-neurotrophins, sortilin, and nociception.Apolipoprotein E receptor pathways in Alzheimer disease.Sorting receptor sortilin-a culprit in cardiovascular and neurological diseases.Informatics Support for Basic Research in Biomedicine.Retromer-Mediated Trafficking of Transmembrane Receptors and Transporters.SorLA complement-type repeat domains protect the amyloid precursor protein against processing.Restoring Soluble Amyloid Precursor Protein α Functions as a Potential Treatment for Alzheimer's Disease.Amyloid beta₁₋₄₂ (Aβ₄₂) up-regulates the expression of sortilin via the p75(NTR)/RhoA signaling pathway.Intracellular itinerary of internalised β-secretase, BACE1, and its potential impact on β-amyloid peptide biogenesis.Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.Calnuc Function in Endosomal Sorting of Lysosomal Receptors.SorCS1 variants and amyloid precursor protein (APP) are co-transported in neurons but only SorCS1c modulates anterograde APP transport.Dissecting the role of sortilin receptor signaling in neurodegeneration induced by NGF deprivation.Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.Complexity and Selectivity of γ-Secretase Cleavage on Multiple Substrates: Consequences in Alzheimer's Disease and Cancer.Trafficking in Alzheimer's Disease: Modulation of APP Transport and Processing by the Transmembrane Proteins LRP1, SorLA, SorCS1c, Sortilin, and Calsyntenin.Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells.Up-regulation of sortilin mediated by amyloid-β and p75(NTR): safety lies in the middle course.Spatiotemporal expression analysis of the growth factor receptor SorCS3.Human sorCS1 binds sortilin and hampers its cellular functions.The A-B-C for SORting APP.
P2860
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P2860
Sortilin and SorLA display distinct roles in processing and trafficking of amyloid precursor protein.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
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2013年學術文章
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2013年學術文章
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name
Sortilin and SorLA display dis ...... of amyloid precursor protein.
@en
Sortilin and SorLA display dis ...... of amyloid precursor protein.
@nl
type
label
Sortilin and SorLA display dis ...... of amyloid precursor protein.
@en
Sortilin and SorLA display dis ...... of amyloid precursor protein.
@nl
prefLabel
Sortilin and SorLA display dis ...... of amyloid precursor protein.
@en
Sortilin and SorLA display dis ...... of amyloid precursor protein.
@nl
P2093
P50
P921
P1476
Sortilin and SorLA display dis ...... g of amyloid precursor protein
@en
P2093
Anders Nykjær
Claus Munck Petersen
Ditte Olsen
Lone Tjener Pallesen
Simon Glerup
P356
10.1523/JNEUROSCI.2371-12.2013
P407
P577
2013-01-01T00:00:00Z