Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice. - Wikidata - wikimedia - TriplyDB

Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.

Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.

http://www.wikidata.org/entity/Q46737437

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New Insights into Podocyte Biology in Glomerular Health and Disease.Kidney Disease in HIV: Moving beyond HIV-Associated Nephropathy.APOL1 variants change C-terminal conformational dynamics and binding to SNARE protein VAMP8.A tripartite complex of suPAR, APOL1 risk variants and αvβ3 integrin on podocytes mediates chronic kidney disease.Apolipoprotein L1 risk variants associate with prevalent atherosclerotic disease in African American systemic lupus erythematosus patients.The genomic landscape of African populations in health and disease.Apolipoprotein L1 confers pH-switchable ion permeability to phospholipid vesicles.Using the Drosophila Nephrocyte to Model Podocyte Function and Disease.ApoL1 Overexpression Drives Variant-Independent Cytotoxicity.Novel avenues for drug discovery in diabetic kidney disease.Exogenous Gene Transmission of Isocitrate Dehydrogenase 2 Mimics Ischemic Preconditioning Protection.APOL1 and Cardiovascular Disease: A Story in Evolution.Linking Race, Cancer Outcomes, and Tissue Repair.Genome-wide association studies of albuminuria: towards genetic stratification in diabetes?Decoding the network of Trypanosoma brucei proteins that determines sensitivity to apolipoprotein-L1.A mouse recapitulating APOL1-associated kidney disease.Kidney disease in the setting of HIV infection: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.Association Between APOL1 Genotypes and Risk of Cardiovascular Disease in MESA (Multi-Ethnic Study of Atherosclerosis).APOL1 and Proteinuria in the AASK: Unraveling the Pathobiology of APOL1.Genetic risk of APOL1 and kidney disease in children and young adults of African ancestry.Modulation of APOL1-miR193a Axis Prevents Podocyte Dediffrentiation in High Glucose Milieu.Application of next-generation sequencing technology to diagnosis and treatment of focal segmental glomerulosclerosis.Plasma biomarkers are associated with renal outcomes in individuals with APOL1 risk variants.UBD modifies APOL1-induced kidney disease risk.APOL1 renal risk variants induce aberrant THP-1 monocyte differentiation and increase eicosanoid production via enhanced expression of cyclooxygenase 2.Molecular Mechanisms of Proteinuria in Focal Segmental Glomerulosclerosis.Assessing known chronic kidney disease associated genetic variants in Saudi Arabian populations.Blocking the 5' splice site of exon 4 by a morpholino oligomer triggers APOL1 protein isoform switch.HIV-associated nephropathy: links, risks and management.Molecular Mechanisms of Injury in HIV-Associated Nephropathy.APOL1-Associated Nephropathy: A Key Contributor to Racial Disparities in CKD APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress APOL1 risk allele RNA contributes to renal toxicity by activating protein kinase R Jagged1/Notch2 controls kidney fibrosis via Tfam-mediated metabolic reprogramming

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Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.

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Ae Seo Deok Park

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Carine M Boustany-Kari

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Chien-An A Hu

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Moin A Saleem

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Differential effects of MYH9 and APOL1 risk variants on FRMD3 Association with Diabetic ESRD in African Americans

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Association of trypanolytic ApoL1 variants with kidney disease in African Americans

APOL1 localization in normal kidney and nondiabetic kidney disease

Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene

Apolipoprotein L1, a novel Bcl-2 homology domain 3-only lipid-binding protein, induces autophagic cell death

ApoL1, a BH3-only lipid-binding protein, induces autophagic cell death

Mice deficient in IL-1 beta-converting enzyme are defective in production of mature IL-1 beta and resistant to endotoxic shock

Functional genomic annotation of genetic risk loci highlights inflammation and epithelial biology networks in CKD

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