Evaluation of valproic acid (VPA) developmental toxicity and pharmacokinetics in Sprague-Dawley rats.
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What We Have Learned about Autism Spectrum Disorder from Valproic AcidEmbryological origin for autism: developmental anomalies of the cranial nerve motor nucleiPrenatal VPA Exposure and Changes in Sensory Processing by the Superior ColliculusEnvironmental enrichment reverses behavioral alterations in rats prenatally exposed to valproic acid: issues for a therapeutic approach in autism.In utero exposure to valproic acid changes sleep in juvenile rats: a model for sleep disturbances in autism.Abnormal emotional learning in a rat model of autism exposed to valproic acid in utero.The transgenerational inheritance of autism-like phenotypes in mice exposed to valproic acid during pregnancy.The intense world syndrome--an alternative hypothesis for autismMode of action: inhibition of histone deacetylase, altering WNT-dependent gene expression, and regulation of beta-catenin--developmental effects of valproic acid.Possible ameliorative effect of breastfeeding and the uptake of human colostrum against coeliac disease in autistic ratsGeneral developmental health in the VPA-rat model of autismMilk transfer and toxicokinetics of valproic Acid in lactating cynomolgus monkeys.Placenta transfer and toxicokinetics of valproic Acid in pregnant cynomolgus monkeys.Teratogenic exposures.Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach.Using zebrafish in systems toxicology for developmental toxicity testing.Comparison of the anticonvulsant efficacies and neurotoxic effects of valproic acid, phenytoin, and the ketogenic diet.Valproic acid attenuates microgliosis in injured spinal cord and purinergic P2X4 receptor expression in activated microglia.The Phosphorylation State of GSK3β Serine 9 Correlated to the Development of Valproic Acid-Associated Fetal Cardiac Teratogenicity, Fetal VPA Syndrome, Rescued by Folic Acid Administration.Molecular approaches to developmental malformations using analogous forms of valproic acid.Stereoselective dysmorphogenicity of the enantiomers of the valproic acid analogue 2-N-propyl-4-pentynoic acid (4-yn-VPA): cross-species evaluation in whole embryo culture.
P2860
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P2860
Evaluation of valproic acid (VPA) developmental toxicity and pharmacokinetics in Sprague-Dawley rats.
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
@wuu
1988年学术文章
@zh-cn
1988年学术文章
@zh-hans
1988年学术文章
@zh-my
1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
@zh
1988年學術文章
@zh-hant
name
Evaluation of valproic acid (V ...... netics in Sprague-Dawley rats.
@en
Evaluation of valproic acid
@nl
type
label
Evaluation of valproic acid (V ...... netics in Sprague-Dawley rats.
@en
Evaluation of valproic acid
@nl
prefLabel
Evaluation of valproic acid (V ...... netics in Sprague-Dawley rats.
@en
Evaluation of valproic acid
@nl
P2093
P1476
Evaluation of valproic acid (V ...... netics in Sprague-Dawley rats.
@en
P2093
P304
P356
10.1016/0272-0590(88)90112-1
P577
1988-10-01T00:00:00Z