A pH-dependent molten globule transition is required for activity of the steroidogenic acute regulatory protein, StAR.
about
The molecular biology, biochemistry, and physiology of human steroidogenesis and its disordersNonclassic congenital lipoid adrenal hyperplasia: a new disorder of the steroidogenic acute regulatory protein with very late presentation and normal male genitaliaImpact of ACTH Signaling on Transcriptional Regulation of Steroidogenic GenesBinding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterolsCharacterization of novel StAR (steroidogenic acute regulatory protein) mutations causing non-classic lipoid adrenal hyperplasiaCellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.Clinical, genetic, and functional characterization of four patients carrying partial loss-of-function mutations in the steroidogenic acute regulatory protein (StAR).Early steps in steroidogenesis: intracellular cholesterol trafficking.Insights into the mechanisms of sterol transport between organelles.STARD4 Membrane Interactions and Sterol Binding.Hormone-induced 14-3-3γ adaptor protein regulates steroidogenic acute regulatory protein activity and steroid biosynthesis in MA-10 Leydig cellsComplex role of the mitochondrial targeting signal in the function of steroidogenic acute regulatory protein revealed by bacterial artificial chromosome transgenesis in vivo.Thirty-Eight-Year Follow-Up of Two Sibling Lipoid Congenital Adrenal Hyperplasia Patients Due to Homozygous Steroidogenic Acute Regulatory (STARD1) Protein Mutation. Molecular Structure and Modeling of the STARD1 L275P Mutation.A brief history of the search for the protein(s) involved in the acute regulation of steroidogenesis.A single cell level measurement of StAR expression and activity in adrenal cells.Cholesterol binding does not predict activity of the steroidogenic acute regulatory protein, StAR.Steroidogenic activity of StAR requires contact with mitochondrial VDAC1 and phosphate carrier protein.Regulation of StAR by the N-terminal Domain and Coinduction of SIK1 and TIS11b/Znf36l1 in Single Cells.STARD6 on steroids: solution structure, multiple timescale backbone dynamics and ligand binding mechanism.Cholesterol interaction with the related steroidogenic acute regulatory lipid-transfer (START) domains of StAR (STARD1) and MLN64 (STARD3).Modeling the structure of the StART domains of MLN64 and StAR proteins in complex with cholesterol.Molecular basis for sterol transport by StART-like lipid transfer domains.
P2860
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P2860
A pH-dependent molten globule transition is required for activity of the steroidogenic acute regulatory protein, StAR.
description
2005 nî lūn-bûn
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2005年の論文
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2005年学术文章
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2005年学术文章
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2005年学术文章
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2005年学术文章
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name
A pH-dependent molten globule ...... cute regulatory protein, StAR.
@en
A pH-dependent molten globule ...... cute regulatory protein, StAR.
@nl
type
label
A pH-dependent molten globule ...... cute regulatory protein, StAR.
@en
A pH-dependent molten globule ...... cute regulatory protein, StAR.
@nl
prefLabel
A pH-dependent molten globule ...... cute regulatory protein, StAR.
@en
A pH-dependent molten globule ...... cute regulatory protein, StAR.
@nl
P2093
P2860
P356
P1476
A pH-dependent molten globule ...... cute regulatory protein, StAR.
@en
P2093
Bo Y Baker
Dustin C Yaworsky
Walter L Miller
P2860
P304
41753-41760
P356
10.1074/JBC.M510241200
P407
P577
2005-10-18T00:00:00Z