Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

Item
http://www.wikidata.org/entity/Q46804369
Unequal efficacy of pyridinium oximes in acute organophosphate poisoning.Design, evaluation and structure-activity relationship studies of the AChE reactivators against organophosphorus pesticides.In Vitro Comparison of Two Most Promising H-Oximes (HI-6 and HLö-7) and Currently Commercially Available Reactivators Pralidoxime and Obidoxime in Reactivation of Cyclosarin-Inhibited Human Cholinesterases.Bisquaternary pyridinium oximes: Comparison of in vitro reactivation potency of compounds bearing aliphatic linkers and heteroaromatic linkers for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase.Reactivation kinetics of 31 structurally different bispyridinium oximes with organophosphate-inhibited human butyrylcholinesterase.New series of monoquaternary pyridinium oximes: Synthesis and reactivation potency for paraoxon-inhibited electric eel and recombinant human acetylcholinesterase.Oxime-dipeptides as anticholinesterase, reactivator of phosphonylated-serine of AChE catalytic triad: probing the mechanistic insight by MM-GBSA, dynamics simulations and DFT analysis.Targeted synthesis of 1-(4-hydroxyiminomethylpyridinium)-3-pyridiniumpropane dibromide--a new nerve agent reactivator.Two step synthesis of a non-symmetric acetylcholinesterase reactivator.Reactivation kinetics of a homologous series of bispyridinium bis-oximes with nerve agent-inhibited human acetylcholinesterase.Potency of five structurally different acetylcholinesterase reactivators to reactivate human brain cholinesterases inhibited by cyclosarin.A newly developed oxime K203 is the most effective reactivator of tabun-inhibited acetylcholinesterase.Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.In Vitro Screening of Blood-Brain Barrier Penetration of Monoquaternary Acetylcholinesterase Reactivators
P2860

Synthesis of the novel series of bispyridinium compounds bearing (E)-but-2-ene linker and evaluation of their reactivation activity against chlorpyrifos-inhibited acetylcholinesterase.

Item
http://www.wikidata.org/entity/Q46804369
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Synthesis of the novel series ...... nhibited acetylcholinesterase.
@en
Synthesis of the novel series of bispyridinium compounds bearing
@nl
type
label
Synthesis of the novel series ...... nhibited acetylcholinesterase.
@en
Synthesis of the novel series of bispyridinium compounds bearing
@nl
prefLabel
Synthesis of the novel series ...... nhibited acetylcholinesterase.
@en
Synthesis of the novel series of bispyridinium compounds bearing
@nl
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
Synthesis of the novel series ...... inhibited acetylcholinesterase
@en
P2093
P304
P31
P356
10.1016/J.BMCL.2005.10.059
P407
P433
P478
P50
P577
P698