BIM and tBID are not mechanistically equivalent when assisting BAX to permeabilize bilayer membranes.
about
Endophilin B1/Bif-1 stimulates BAX activation independently from its capacity to produce large scale membrane morphological rearrangementsMitochondrial apoptosis and BH3 mimeticsPermeabilization of the mitochondrial outer membrane by Bax/truncated Bid (tBid) proteins as sensitized by cardiolipin hydroperoxide translocation: mechanistic implications for the intrinsic pathway of oxidative apoptosisBax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranesUnravelling the bcl-2 apoptosis code with a simple model system.Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.How do BCL-2 proteins induce mitochondrial outer membrane permeabilization?Protein kinase networks regulating glucocorticoid-induced apoptosis of hematopoietic cancer cells: fundamental aspects and practical considerations.Emerging understanding of Bcl-2 biology: Implications for neoplastic progression and treatment.Inhibition of Drp1 provides neuroprotection in vitro and in vivo.A novel BH3 mimetic S1 potently induces Bax/Bak-dependent apoptosis by targeting both Bcl-2 and Mcl-1.Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size.Reconstitution of proapoptotic BAK function in liposomes reveals a dual role for mitochondrial lipids in the BAK-driven membrane permeabilization processMechanisms by which Bak and Bax permeabilise mitochondria during apoptosis.BAX insertion, oligomerization, and outer membrane permeabilization in brain mitochondria: role of permeability transition and SH-redox regulation.Membrane insertion of the BAX core, but not latch domain, drives apoptotic pore formation.Mcl-1 and Bcl-xL sequestration of Bak confers differential resistance to BH3-only proteins.JNK3 phosphorylates Bax protein and induces ability to form pore on bilayer lipid membrane.
P2860
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P2860
BIM and tBID are not mechanistically equivalent when assisting BAX to permeabilize bilayer membranes.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
BIM and tBID are not mechanist ...... ermeabilize bilayer membranes.
@en
BIM and tBID are not mechanist ...... ermeabilize bilayer membranes.
@nl
type
label
BIM and tBID are not mechanist ...... ermeabilize bilayer membranes.
@en
BIM and tBID are not mechanist ...... ermeabilize bilayer membranes.
@nl
prefLabel
BIM and tBID are not mechanist ...... ermeabilize bilayer membranes.
@en
BIM and tBID are not mechanist ...... ermeabilize bilayer membranes.
@nl
P2093
P2860
P356
P1476
BIM and tBID are not mechanist ...... ermeabilize bilayer membranes.
@en
P2093
Aitor Etxebarria
Ane Landajuela
Bruno Antonsson
Gorka Basañez
Oihana Terrones
Olatz Landeta
P2860
P304
P356
10.1074/JBC.M708814200
P407
P577
2008-01-14T00:00:00Z