PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis. - Wikidata - wikimedia - TriplyDB

PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis.

PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis.

http://www.wikidata.org/entity/Q46830543

about

The triterpenoid CDDO-Me inhibits bleomycin-induced lung inflammation and fibrosis Fibroblasts in fibrosis: novel roles and mediators The wound healing, chronic fibrosis, and cancer progression triad PPARγ as a Novel Therapeutic Target in Lung Cancer Rosiglitazone prevents high glucose-induced vascular endothelial growth factor and collagen IV expression in cultured mesangial cells.MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis.PPARγ downregulation by TGFß in fibroblast and impaired expression and function in systemic sclerosis: a novel mechanism for progressive fibrogenesis Effects of PPAR gamma ligands on TGF-beta1-induced epithelial-mesenchymal transition in alveolar epithelial cells.PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis.Inhibition of transglutaminase 2, a novel target for pulmonary fibrosis, by two small electrophilic molecules.Peroxisome proliferator-activated receptor (PPAR)gamma can inhibit chronic renal allograft damage Innovative approaches to the therapy of fibrosis Curcumin inhibits fibrosis-related effects in IPF fibroblasts and in mice following bleomycin-induced lung injury Efficacies of rosiglitazone and retinoin on bleomycin-induced pulmonary fibrosis in rats.Peroxisome proliferator-activated receptor-g agonist treatment increases septation and angiogenesis and decreases airway hyperresponsiveness in a model of experimental neonatal chronic lung disease.Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice Pioglitazone Attenuates Cystic Burden in the PCK Rodent Model of Polycystic Kidney Disease.Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism.Regulation of fibroblast lipid storage and myofibroblast phenotypes during alveolar septation in mice Nitrated fatty acids reverse pulmonary fibrosis by dedifferentiating myofibroblasts and promoting collagen uptake by alveolar macrophages.The Antifibrosis Effects of Peroxisome Proliferator-Activated Receptor δ on Rat Corneal Wound Healing after Excimer Laser Keratectomy Hypoxia-induced inhibition of lung development is attenuated by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone.Integrating mechanisms of pulmonary fibrosis Carbon-nanoparticle-triggered acute lung inflammation and its resolution are not altered in PPARγ-defective (P465L) mice.The PPARγ Agonist Rosiglitazone Is Antifibrotic for Scleroderma Lung Fibroblasts: Mechanisms of Action and Differential Racial Effects.A breath of fresh air on the mesenchyme: impact of impaired mesenchymal development on the pathogenesis of bronchopulmonary dysplasia.Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling.Leptin promotes fibroproliferative acute respiratory distress syndrome by inhibiting peroxisome proliferator-activated receptor-γ Peroxisome proliferator-activated receptor γ: innate protection from excessive fibrogenesis and potential therapeutic target in systemic sclerosis Sex differences and sex steroids in lung health and disease.Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases.Regulation of Matrix Remodeling by Peroxisome Proliferator-Activated Receptor-γ: A Novel Link Between Metabolism and Fibrogenesis.Altered DNA methylation profile in idiopathic pulmonary fibrosis.Dynamic regulation of platelet-derived growth factor receptor α expression in alveolar fibroblasts during realveolarization PPARγ activation following apoptotic cell instillation promotes resolution of lung inflammation and fibrosis via regulation of efferocytosis and proresolving cytokines.Proteasomal inhibition after injury prevents fibrosis by modulating TGF-β(1) signalling.Mechanisms of Lung Fibrosis Resolution.Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gamma Role of peroxisome proliferator-activated receptor gamma and its ligands in the treatment of hematological malignancies Activation of PPARγ by Rosiglitazone does not negatively impact male sex steroid hormones in diabetic rats.

P2860

Q21559629-D24BD393-547A-49C7-982C-091E51FAD591 Q26998508-2922C9E1-3588-4183-8C36-D6FDCD612423 Q27014616-F99F29A1-EADF-4A8E-A2FD-79542F55486D Q28068114-EDFDF03A-C025-4725-B8BC-8C45CF9F0771 Q29347056-A3DE964B-1381-4008-8A18-51E8EEAD63A0 Q33643242-DFBE900B-05ED-46D7-AFBB-E2AE58FCBE1B Q33745028-F5B1D95A-00EE-429C-9E97-29DA9AD06ECC Q33748854-CDA2CE06-3555-423B-A0DB-631F7BFA4B72 Q33799182-90D0001F-7B23-41BA-A682-FBAD24AC1E6D Q33799573-A54012E9-D2D9-4DFA-A4EA-D44FDDA4B11A Q33816291-59FD7725-1224-4FD9-ABA7-B145ABC9D992 Q33824140-56E652FB-B73C-452A-A7D1-8654B3346D2D Q33840489-4D2AE6CD-3021-407C-896B-523F35B2EAE8 Q33847144-A00A46AC-9236-4E08-97C7-E14DAB08A8CB Q33863173-6B253953-2F52-423C-91AF-47636025B4D6 Q34032853-CCFBDBE1-A675-40EA-8A48-7B8F8A28FCD5 Q34260759-01397DA3-7AAC-4F2D-A461-17689B7E3C42 Q34321160-CAF3142A-F7B7-4B1F-BFB4-DB0F04474094 Q34356467-C98BFA34-F485-41CB-A71B-76BC3E197705 Q34512881-43B71C32-7F94-4E2F-8DEF-BF9A6B9CF339 Q34590539-B4DBA871-68DA-4311-9754-95BC36A12610 Q35087009-96BD472B-F56A-4B2B-BA8A-3952EB2DDEB5 Q35106452-49D3F484-A86B-44F0-B94B-A2AB788F8DE5 Q35397274-D37D52D6-68CE-4C82-8FA5-0E735D0D93E2 Q35503543-CD6D59A4-4ABE-43EC-9157-AE579D7FCAFE Q35545614-38D94382-9B1B-4C0E-B117-21E536884287 Q35601455-672ED1ED-80A9-4D88-B0B9-806CFE5135A8 Q35694487-C4279CC7-7923-42E7-90FF-B5409D7A4F3C Q35954579-10B7C457-660F-438E-88E8-5369ABD4668A Q36003356-C6CF67C6-4D61-4F85-9F6F-552AFDEFE749 Q36063833-6D42E141-EE55-4892-8C2D-116721AAAC7A Q36093802-30550408-4C5D-4CD7-901F-6167006724AE Q36345274-2A48DC59-E57A-4B37-98EA-38A17EB9C92A Q36369940-23070549-1D69-4828-858A-0573F14F0424 Q36605155-1F67A2B0-35AC-4ACC-8152-40C450564891 Q36678523-1076FAB8-A571-4490-A017-894192517A6B Q36885732-6BEF9E8D-0B6C-4D3D-A632-5BB52B88DF5C Q37071874-62EC5929-CB97-4607-B7E6-0F03F77A6DCD Q37182794-7ED13294-DB94-4029-896C-E23DD45D2CE4 Q37226962-5E5CD619-4AD0-4EE7-AF04-7FB81C24EF0A

P2860

PPAR-gamma agonists inhibit profibrotic phenotypes in human lung fibroblasts and bleomycin-induced pulmonary fibrosis.

http://www.wikidata.org/entity/Q46830543

description

2007 nî lūn-bûn

@nan

2007年の論文

@ja

2007年学术文章

@wuu

2007年学术文章

@zh

2007年学术文章

@zh-cn

2007年学术文章

@zh-hans

2007年学术文章

@zh-my

2007年学术文章

@zh-sg

2007年學術文章

@yue

2007年學術文章

@zh-hant

name

PPAR-gamma agonists inhibit pr ...... in-induced pulmonary fibrosis.

@en

PPAR-gamma agonists inhibit pr ...... in-induced pulmonary fibrosis.

@nl

type

label

PPAR-gamma agonists inhibit pr ...... in-induced pulmonary fibrosis.

@en

PPAR-gamma agonists inhibit pr ...... in-induced pulmonary fibrosis.

@nl

prefLabel

PPAR-gamma agonists inhibit pr ...... in-induced pulmonary fibrosis.

@en

PPAR-gamma agonists inhibit pr ...... in-induced pulmonary fibrosis.

@nl

P1433

Q46830543-D448940D-54DD-4990-AF3A-08C02A63A317

P1476

Q46830543-AA870B8C-7B85-4A81-81C1-43846C58F15F

P2093

Q46830543-55995CFB-A2A7-4A0D-A245-74B898F19A62

Q46830543-59F2160A-A008-4A34-BCC8-C85DB40BB927

Q46830543-5DD90087-6329-4264-9AF0-2B1A95BCBF46

Q46830543-75DA3EBC-E227-4EE5-A4A1-554B5212833A

Q46830543-800714E6-A32B-4247-8E9F-0C40D0895BD6

Q46830543-C5B7F628-FD0D-409E-8D3F-6DB73E46889A

Q46830543-EE782079-1EFA-4B69-8DA2-4E965BB9FFCE

Q46830543-FD830F7B-75BD-47D1-9F2F-BFACD112B052

P2860

Q46830543-01AED8CD-4A11-4AA9-882B-6DD729211DDD

Q46830543-0287EA01-8376-4142-9BB9-B6AAC9A698D9

Q46830543-0993F5B1-BF45-4D7A-8D06-91302A9DDFF2

Q46830543-0A4A76C5-7880-4BE5-9884-594ED2BE103A

Q46830543-0CDBB6EC-54C7-4B3B-9808-7D2E6D9E4065

Q46830543-0DD51267-EB3E-413B-A22D-52D0751D4509

Q46830543-13243AFF-7EFA-46AA-AAA5-58483B9210A3

Q46830543-21D0C7A9-9553-4A5F-9585-10AA4B8073DA

Q46830543-23881550-D883-41B0-A90C-A3E31BDBEAC6

Q46830543-262D84E0-0CFF-44FE-8417-9BA8B267BF6B

P304

Q46830543-2D56EA8B-1FBA-49E7-AD18-F7416CA59C81

P31

Q46830543-0B8FBF8B-E4E4-4C11-96F0-EABF8EA7796C

P356

Q46830543-6A989F69-5EC2-44F4-8406-C95EB81D3D86

P433

Q46830543-6A05D5F9-063E-4429-8740-AFF14F656DEF

P478

Q46830543-6A797874-47C2-4636-B850-266B23257A35

P50

Q46830543-77DEDFBF-2336-48AA-9E95-A6258EBA53BB

P577

Q46830543-F61C237E-35CC-4E02-BB0F-BCBA1C3C4D86

P5875

Q46830543-F0F805C5-EEEA-4BDB-A151-24325C9E0B9D

P698

Q46830543-93D74115-1BDF-48FD-BC36-D757A339B070

P921

Q46830543-90ACD902-E840-40ED-9FD1-C3469600534F

P932

Q46830543-23D2C692-9EE6-4F22-9587-33B6C68F3ABE

P356

AJPLUNG.00333.2007

P1433

American Journal of Physiology - Lung Cellular and Molecular Physiology

P1476

PPAR-gamma agonists inhibit pr ...... in-induced pulmonary fibrosis.

@en

P2093

Biao Hu

http://www.w3.org/2001/XMLSchema#string

Cory M Hogaboam

http://www.w3.org/2001/XMLSchema#string

Jami E Milam

http://www.w3.org/2001/XMLSchema#string

Raju C Reddy

http://www.w3.org/2001/XMLSchema#string

Srinivasa R Gangireddy

http://www.w3.org/2001/XMLSchema#string

Theodore J Standiford

http://www.w3.org/2001/XMLSchema#string

Venkateshwar G Keshamouni

http://www.w3.org/2001/XMLSchema#string

Victor J Thannickal

http://www.w3.org/2001/XMLSchema#string

P2860

Shared expression of phenotypic markers in systemic sclerosis indicates a convergence of pericytes and fibroblasts to a myofibroblast lineage in fibrosis

The pathophysiological function of peroxisome proliferator-activated receptor-gamma in lung-related diseases.

The mechanisms of action of PPARs

Agonists of peroxisome proliferators-activated receptors (PPAR) alpha, beta/delta or gamma reduce transforming growth factor (TGF)-beta-induced proteoglycans' production in chondrocytes

Unique ability of troglitazone to up-regulate peroxisome proliferator-activated receptor-gamma expression in hepatocytes

Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase

Proteomic study of plasma proteins in pregnant women with asthma.

Genome-wide identification of peroxisome proliferator response elements using integrated computational genomics.

Pharmacologic therapy for type 2 diabetes mellitus.

Pleuropulmonary manifestations of systemic lupus erythematosus.

P304

L891-901

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1152/AJPLUNG.00333.2007

http://www.w3.org/2001/XMLSchema#string

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

294

http://www.w3.org/2001/XMLSchema#string

P50

P577

2007-12-27T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5686149

http://www.w3.org/2001/XMLSchema#string

P698

18162602

http://www.w3.org/2001/XMLSchema#string

P921

pulmonary fibrosis

P932

5926773

http://www.w3.org/2001/XMLSchema#string