Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures.
about
Interdiction of sphingolipid metabolism to improve standard cancer therapies.Low sphingosine-1-phosphate plasma levels are predictive for increased mortality in patients with liver cirrhosis.PDGF induces SphK1 expression via Egr-1 to promote pulmonary artery smooth muscle cell proliferation.Sphingosine-1-phosphate acts as a key molecule in the direct mediation of renal fibrosis.Dissecting fibrosis: therapeutic insights from the small-molecule toolbox.The platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) are major players in oncogenesis, drug resistance, and attractive oncologic targets in cancer.FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease.Essential roles of sphingosine 1-phosphate receptor types 1 and 3 in human hepatic stellate cells motility and activation.Sphingosine 1-Phosphate Signaling as a Target in Hepatic Fibrosis Therapy.Divergent Role of Sphingosine 1-Phosphate in Liver Health and Disease.
P2860
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P2860
Cross-talk between PDGF and S1P signalling elucidates the inhibitory effect and potential antifibrotic action of the immunomodulator FTY720 in activated HSC-cultures.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Cross-talk between PDGF and S1 ...... 720 in activated HSC-cultures.
@en
Cross-talk between PDGF and S1 ...... 720 in activated HSC-cultures.
@nl
type
label
Cross-talk between PDGF and S1 ...... 720 in activated HSC-cultures.
@en
Cross-talk between PDGF and S1 ...... 720 in activated HSC-cultures.
@nl
prefLabel
Cross-talk between PDGF and S1 ...... 720 in activated HSC-cultures.
@en
Cross-talk between PDGF and S1 ...... 720 in activated HSC-cultures.
@nl
P2093
P50
P1476
Cross-talk between PDGF and S1 ...... Y720 in activated HSC-cultures
@en
P2093
Amedeo Carraro
Antonio Toninello
Elena Tibaldi
Giovanna Nalesso
Maria Lina Massimino
P304
P356
10.1016/J.BBAMCR.2007.11.008
P577
2007-11-29T00:00:00Z