DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains.
about
Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structureIn vitro and in vivo interactions of DNA ligase IV with a subunit of the condensin complexPhosphorylation and regulation of DNA ligase IV stability by DNA-dependent protein kinaseDNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activityCrystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.Crystal structure of the Xrcc4 DNA repair protein and implications for end joiningEukaryotic DNA ligases: structural and functional insightsStructural and functional interaction between the human DNA repair proteins DNA ligase IV and XRCC4Genetic variants of NHEJ DNA ligase IV can affect the risk of developing multiple myeloma, a tumour characterised by aberrant class switch recombinationModes of interaction among yeast Nej1, Lif1 and Dnl4 proteins and comparison to human XLF, XRCC4 and Lig4ATP-dependent DNA ligasesSister chromatid decatenation: bridging the gaps in our knowledgeDNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining systemRole of non-homologous end joining in V(D)J recombinationNovel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.Positive selection on the nonhomologous end-joining factor Cernunnos-XLF in the human lineageExtreme growth failure is a common presentation of ligase IV deficiency.Nonhomologous end joining: a good solution for bad endsRad18 is required for DNA repair and checkpoint responses in fission yeast.DNA Ligase IV regulates XRCC4 nuclear localization.Mechanisms of double-strand break repair in somatic mammalian cells.XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms.The Drosophila melanogaster DNA Ligase IV gene plays a crucial role in the repair of radiation-induced DNA double-strand breaks and acts synergistically with Rad54Genetic polymorphisms of DNA double-strand break repair pathway genes and glioma susceptibility.Yeast DNA ligase IV mutations reveal a nonhomologous end joining function of BRCT1 distinct from XRCC4/Lif1 binding.Choosing the right path: does DNA-PK help make the decision?Ionizing radiation-induced XRCC4 phosphorylation is mediated through ATM in addition to DNA-PK.Genetic variants of the nonhomologous end joining gene LIG4 and severe radiation pneumonitis in nonsmall cell lung cancer patients treated with definitive radiotherapy.The α2 helix in the DNA ligase IV BRCT-1 domain is required for targeted degradation of ligase IV during adenovirus infection.Structure-Based Virtual Ligand Screening on the XRCC4/DNA Ligase IV Interface.Ovarian cancer and DNA repair: DNA ligase IV as a potential key.V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining.DNA double-strand break repair and development.Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining.Different DNA End Configurations Dictate Which NHEJ Components Are Most Important for Joining Efficiency.Reversion of the ErbB malignant phenotype and the DNA damage response.The spatial organization of non-homologous end joining: from bridging to end joining.Quality control of homologous recombination.Genetic evidence for the involvement of DNA ligase IV in the DNA-PK-dependent pathway of non-homologous end joining in mammalian cells.
P2860
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P2860
DNA ligase IV binds to XRCC4 via a motif located between rather than within its BRCT domains.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh-hant
name
DNA ligase IV binds to XRCC4 v ...... than within its BRCT domains.
@en
DNA ligase IV binds to XRCC4 v ...... than within its BRCT domains.
@nl
type
label
DNA ligase IV binds to XRCC4 v ...... than within its BRCT domains.
@en
DNA ligase IV binds to XRCC4 v ...... than within its BRCT domains.
@nl
prefLabel
DNA ligase IV binds to XRCC4 v ...... than within its BRCT domains.
@en
DNA ligase IV binds to XRCC4 v ...... than within its BRCT domains.
@nl
P2093
P1433
P1476
DNA ligase IV binds to XRCC4 v ...... than within its BRCT domains.
@en
P2093
P304
P356
10.1016/S0960-9822(07)00349-1
P407
P577
1998-07-01T00:00:00Z