Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels.
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Induction of kinase suppressor of RAS-1(KSR-1) gene by 1, alpha25-dihydroxyvitamin D3 in human leukemia HL60 cells through a vitamin D response element in the 5'-flanking regionATRA-induced cellular differentiation and CD38 expression inhibits acquisition of BCR-ABL mutations for CML acquired resistanceArsenic trioxide cooperates with all trans retinoic acid to enhance mitogen-activated protein kinase activation and differentiation in PML-RARalpha negative human myeloblastic leukemia cells.Phosphorylation of c-Cbl and p85 PI3K driven by all-trans retinoic acid and CD38 depends on Lyn kinase activity.The Src-family kinase inhibitor PP2 rescues inducible differentiation events in emergent retinoic acid-resistant myeloblastic leukemia cells.Retinoic acid therapy resistance progresses from unilineage to bilineage in HL-60 leukemic blasts.6-Formylindolo(3,2-b)Carbazole (FICZ) Modulates the Signalsome Responsible for RA-Induced Differentiation of HL-60 Myeloblastic Leukemia Cells.ATRA-induced HL-60 myeloid leukemia cell differentiation depends on the CD38 cytosolic tail needed for membrane localization, but CD38 enzymatic activity is unnecessary.c-Cbl tyrosine kinase-binding domain mutant G306E abolishes the interaction of c-Cbl with CD38 and fails to promote retinoic acid-induced cell differentiation and G0 arrestRRD-251 enhances all-trans retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells.A MAPK-positive feedback mechanism for BLR1 signaling propels retinoic acid-triggered differentiation and cell cycle arrest.c-Cbl interacts with CD38 and promotes retinoic acid-induced differentiation and G0 arrest of human myeloblastic leukemia cells.The leukemogenic fusion gene MLL-AF9 alters microRNA expression pattern and inhibits monoblastic differentiation via miR-511 repression.Interferon regulatory factor-1 binds c-Cbl, enhances mitogen activated protein kinase signaling and promotes retinoic acid-induced differentiation of HL-60 human myelo-monoblastic leukemia cells.Revealing CD38 cellular localization using a cell permeable, mechanism-based fluorescent small-molecule probe.Induction of retinoid X receptor activity and consequent upregulation of p21WAF1/CIP1 by indenoisoquinolines in MCF7 cells.Expression of CD38 in human neuroblastoma SH-SY5Y cells.Retinoic acid induces nuclear accumulation of Raf1 during differentiation of HL-60 cells.Human myeloblastic leukemia cells (HL-60) express a membrane receptor for estrogen that signals and modulates retinoic acid-induced cell differentiation.Nicotinamide cooperates with retinoic acid and 1,25-dihydroxyvitamin D(3) to regulate cell differentiation and cell cycle arrest of human myeloblastic leukemia cells.Mechanism-based small molecule probes for labeling CD38 on live cells.Probing the requirement for CD38 in retinoic acid-induced HL-60 cell differentiation with a small molecule dimerizer and genetic knockout.Synergistic and additive effect of retinoic acid in circumventing resistance to p53 restoration.Potential for subsets of wt-NPM1 primary AML blasts to respond to retinoic acid treatment.Src family kinase inhibitor bosutinib enhances retinoic acid-induced differentiation of HL-60 leukemia cells.
P2860
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P2860
Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Retinoic acid-induced CD38 exp ...... epending on expression levels.
@en
Retinoic acid-induced CD38 exp ...... epending on expression levels.
@nl
type
label
Retinoic acid-induced CD38 exp ...... epending on expression levels.
@en
Retinoic acid-induced CD38 exp ...... epending on expression levels.
@nl
prefLabel
Retinoic acid-induced CD38 exp ...... epending on expression levels.
@en
Retinoic acid-induced CD38 exp ...... epending on expression levels.
@nl
P2093
P356
P1476
Retinoic acid-induced CD38 exp ...... depending on expression levels
@en
P2093
Andrew Yen
James L Smith
R Michael Sramkoski
Susi Varvayanis
Thomas J Lamkin
Vivian Chin
P304
P356
10.1002/JCB.20745
P577
2006-04-01T00:00:00Z