Up-regulation of CPI-17 phosphorylation in diabetic vasculature and high glucose cultured vascular smooth muscle cells.
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Regulation of cellular protein phosphatase-1 (PP1) by phosphorylation of the CPI-17 family, C-kinase-activated PP1 inhibitorsPhosphorylation-induced conformational switching of CPI-17 produces a potent myosin phosphatase inhibitorThe Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular DiseaseIdentification of a cAMP-response element in the regulator of G-protein signaling-2 (RGS2) promoter as a key cis-regulatory element for RGS2 transcriptional regulation by angiotensin II in cultured vascular smooth musclesRole of calcium-independent phospholipase A2beta in high glucose-induced activation of RhoA, Rho kinase, and CPI-17 in cultured vascular smooth muscle cells and vascular smooth muscle hypercontractility in diabetic animals.Increased cytochrome P4502E1 expression and altered hydroxyeicosatetraenoic acid formation mediate diabetic vascular dysfunction: rescue by guanylyl-cyclase activation.Emerging roles of the myocardin family of proteins in lipid and glucose metabolism.Impaired coronary microvascular dilation correlates with enhanced vascular smooth muscle MLC phosphorylation in diabetesSmooth-muscle BMAL1 participates in blood pressure circadian rhythm regulation.Elevated Glucose Levels Promote Contractile and Cytoskeletal Gene Expression in Vascular Smooth Muscle via Rho/Protein Kinase C and Actin PolymerizationAltered clock gene expression and vascular smooth muscle diurnal contractile variations in type 2 diabetic db/db mice.Smooth muscle-specific expression of calcium-independent phospholipase A2β (iPLA2β) participates in the initiation and early progression of vascular inflammation and neointima formationGroup VIA phospholipase A2 (iPLA2beta) participates in angiotensin II-induced transcriptional up-regulation of regulator of g-protein signaling-2 in vascular smooth muscle cells.Diabetes-induced increased oxidative stress in cardiomyocytes is sustained by a positive feedback loop involving Rho kinase and PKCβ2.GATA-6 and NF-κB activate CPI-17 gene transcription and regulate Ca2+ sensitization of smooth muscle contractionSmooth muscle-selective CPI-17 expression increases vascular smooth muscle contraction and blood pressureAcute Rho-kinase inhibition improves coronary dysfunction in vivo, in the early diabetic microcirculationTargeting of Rho kinase ameliorates impairment of diabetic endothelial function in intrarenal artery.Long-term diabetic complications may be ameliorated by targeting Rho kinase.Targeting endothelial dysfunction in vascular complications associated with diabetes.Novel contributions of the smoothelin-like 1 protein in vascular smooth muscle contraction and its potential involvement in myogenic tone.Role of ROCK upregulation in endothelial and smooth muscle vascular functions in diabetic rat aorta.Diabetes-induced oxidative stress mediates upregulation of RhoA/Rho kinase pathway and hypercontractility of gastric smooth muscle.Spontaneous activity and stretch-induced contractile differentiation are reduced in vascular smooth muscle of miR-143/145 knockout mice.Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats.RhoA-Rho kinase signaling mediates endothelium- and endoperoxide-dependent contractile activities characteristic of hypertensive vascular dysfunction.Sex-dependent differences in Rho activation contribute to contractile dysfunction in type 2 diabetic mice.High glucose enhances responsiveness of human airways smooth muscle via the Rho/ROCK pathway.Weight and inflammation are the major determinants of vascular dysfunction in the aortae of db/db mice.Dietary Supplement of Large Yellow Tea Ameliorates Metabolic Syndrome and Attenuates Hepatic Steatosis in db/db Mice.Toll-like receptor 2 mediates vascular contraction and activates RhoA signaling in vascular smooth muscle cells from STZ-induced type 1 diabetic rats.Voluntary wheel running ameliorates vascular smooth muscle hyper-contractility in type 2 diabetic db/db micePreventive Effect of Flavonol Derivatives Abundant Sanglan Tea on Long-Term High-Fat-Diet-Induced Obesity Complications in C57BL/6 Mice
P2860
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P2860
Up-regulation of CPI-17 phosphorylation in diabetic vasculature and high glucose cultured vascular smooth muscle cells.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Up-regulation of CPI-17 phosph ...... vascular smooth muscle cells.
@en
Up-regulation of CPI-17 phosph ...... vascular smooth muscle cells.
@nl
type
label
Up-regulation of CPI-17 phosph ...... vascular smooth muscle cells.
@en
Up-regulation of CPI-17 phosph ...... vascular smooth muscle cells.
@nl
prefLabel
Up-regulation of CPI-17 phosph ...... vascular smooth muscle cells.
@en
Up-regulation of CPI-17 phosph ...... vascular smooth muscle cells.
@nl
P2093
P1476
Up-regulation of CPI-17 phosph ...... d vascular smooth muscle cells
@en
P2093
Ming C Gong
Zhenheng Guo
Zhongwen Xie
P304
P356
10.1016/J.CARDIORES.2005.11.002
P577
2005-12-05T00:00:00Z