Chimeric mice with hepatocyte-humanized liver as an appropriate model to study human peroxisome proliferator-activated receptor-α.
about
The truncated splice variant of peroxisome proliferator-activated receptor alpha, PPARα-tr, autonomously regulates proliferative and pro-inflammatory genesThe Promise of New Technologies to Reduce, Refine, or Replace Animal Use while Reducing Risks of Drug Induced Liver Injury in Pharmaceutical Development.Preclinical models for interrogating drug action in human cancers using Stable Isotope Resolved Metabolomics (SIRM).Preclinical Characterization and Human Microdose Pharmacokinetics of ITMN-8187, a Nonmacrocyclic Inhibitor of the Hepatitis C Virus NS3 Protease.The PPARα-dependent rodent liver tumor response is not relevant to humans: addressing misconceptions.The Peroxisome Proliferator-Activated Receptor α is dispensable for cold-induced adipose tissue browning in mice.The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized mice.Testing the PPAR hypothesis of tobacco use disorder in humans: A randomized trial of the impact of gemfibrozil (a partial PPARα agonist) in smokers
P2860
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P2860
Chimeric mice with hepatocyte-humanized liver as an appropriate model to study human peroxisome proliferator-activated receptor-α.
description
2014 nî lūn-bûn
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name
Chimeric mice with hepatocyte- ...... iferator-activated receptor-α.
@en
Chimeric mice with hepatocyte- ...... iferator-activated receptor-α.
@nl
type
label
Chimeric mice with hepatocyte- ...... iferator-activated receptor-α.
@en
Chimeric mice with hepatocyte- ...... iferator-activated receptor-α.
@nl
prefLabel
Chimeric mice with hepatocyte- ...... iferator-activated receptor-α.
@en
Chimeric mice with hepatocyte- ...... iferator-activated receptor-α.
@nl
P2093
P2860
P356
P1476
Chimeric mice with hepatocyte- ...... iferator-activated receptor-α.
@en
P2093
Chihiro Yamasaki
Chise Tateno
Katsutoshi Yoshizato
Ken Oofusa
Miyoko Okada
Naohisa Tsutsui
Toshinobu Yamamoto
Yuji Ishida
Yuka Myoken
P2860
P304
P356
10.1177/0192623314544378
P407
P577
2014-08-08T00:00:00Z