Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression.
about
Androgen deprivation-induced senescence promotes outgrowth of androgen-refractory prostate cancer cellsRepression of androgen receptor activity by HEYL, a third member of the Hairy/Enhancer-of-split-related family of Notch effectorsSelective androgen receptor modulators in preclinical and clinical developmentAdvances in genetics: widening our understanding of prostate cancerCentral role for PELP1 in nonandrogenic activation of the androgen receptor in prostate cancerSystematic structure-function analysis of androgen receptor Leu701 mutants explains the properties of the prostate cancer mutant L701H.Modulation of androgen receptor signaling in hormonal therapy-resistant prostate cancer cell linesMolecular genetics of prostate cancer: new prospects for old challengesThe impact of point mutations in the human androgen receptor: classification of mutations on the basis of transcriptional activityMiR137 is an androgen regulated repressor of an extended network of transcriptional coregulators.Minireview: Alternative activation pathways for the androgen receptor in prostate cancer.Expression and function of nuclear receptor co-activator 4: evidence of a potential role independent of co-activator activity.An androgen response element driven reporter assay for the detection of androgen receptor activity in prostate cells.A novel androgen receptor amino terminal region reveals two classes of amino/carboxyl interaction-deficient variants with divergent capacity to activate responsive sites in chromatin.Diverse roles of androgen receptor (AR) domains in AR-mediated signaling.Cellular androgen content influences enzalutamide agonism of F877L mutant androgen receptor.The role of androgen receptor mutations in prostate cancer progression.Ligand-independent and tissue-selective androgen receptor inhibition by pyrvinium.New strategies for medical management of castration-resistant prostate cancer.The changing therapeutic landscape of castration-resistant prostate cancer.Binding of bisphenol A, bisphenol AF, and bisphenol S on the androgen receptor: Coregulator recruitment and stimulation of potential interaction sites.Critical role of androgen receptor level in prostate cancer cell resistance to new generation antiandrogen enzalutamide.Development and exploitation of a novel mutant androgen receptor modelling strategy to identify new targets for advanced prostate cancer therapy.Antiandrogens act as selective androgen receptor modulators at the proteome level in prostate cancer cells.Androgen receptor variation affects prostate cancer progression and drug resistance.Engineered repressors are potent inhibitors of androgen receptor activity.Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration-resistant prostate cancer.ERK and AKT signaling drive MED1 overexpression in prostate cancer in association with elevated proliferation and tumorigenicity.Role of the HSP90-associated cochaperone p23 in enhancing activity of the androgen receptor and significance for prostate cancerPrx1 enhances androgen receptor function in prostate cancer cells by increasing receptor affinity to dihydrotestosterone.The context of prostate cancer genomics in personalized medicine.Androgen receptor gene mutation, rearrangement, polymorphism.Determining direct binders of the Androgen Receptor using a high-throughput Cellular Thermal Shift Assay.
P2860
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P2860
Mechanisms of androgen receptor activation in advanced prostate cancer: differential co-activator recruitment and gene expression.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Mechanisms of androgen recepto ...... cruitment and gene expression.
@en
Mechanisms of androgen recepto ...... cruitment and gene expression.
@nl
type
label
Mechanisms of androgen recepto ...... cruitment and gene expression.
@en
Mechanisms of androgen recepto ...... cruitment and gene expression.
@nl
prefLabel
Mechanisms of androgen recepto ...... cruitment and gene expression.
@en
Mechanisms of androgen recepto ...... cruitment and gene expression.
@nl
P2860
P356
P1433
P1476
Mechanisms of androgen recepto ...... ecruitment and gene expression
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1210955
P407
P577
2007-11-26T00:00:00Z