Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites.
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Identification of a functional docking site in the Rpn1 LRR domain for the UBA-UBL domain protein Ddi1A protein interaction network for Ecm29 links the 26 S proteasome to molecular motors and endosomal componentsChaperone-mediated pathway of proteasome regulatory particle assemblyThe life cycle of the 26S proteasome: from birth, through regulation and function, and onto its deathMitochondrial and Ubiquitin Proteasome System Dysfunction in Ageing and Disease: Two Sides of the Same Coin?Regulation of the proteasome by ATP: implications for ischemic myocardial injury and donor heart preservationStructure of a Proteasome Pba1-Pba2 Complex: IMPLICATIONS FOR PROTEASOME ASSEMBLY, ACTIVATION, AND BIOLOGICAL FUNCTIONDifferential global structural changes in the core particle of yeast and mouse proteasome induced by ligand bindingMolecular architecture and assembly of the eukaryotic proteasomeBlm10 facilitates nuclear import of proteasome core particlesStructural defects in the regulatory particle-core particle interface of the proteasome induce a novel proteasome stress responseProteasome assemblyAn asymmetric interface between the regulatory and core particles of the proteasomeProteasome inhibitors alter levels of intracellular peptides in HEK293T and SH-SY5Y cellsChronic ethanol feeding affects proteasome-interacting proteinsPAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasisRecognition and processing of ubiquitin-protein conjugates by the proteasomeLong-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs.PA28αβ: the enigmatic magic ring of the proteasome?Characterization of the Brain 26S Proteasome and its Interacting ProteinsAssembly, structure, and function of the 26S proteasome.Affinity purification of the Arabidopsis 26 S proteasome reveals a diverse array of plant proteolytic complexes.Inherent asymmetry in the 26S proteasome is defined by the ubiquitin receptor RPN13Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway.A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor bindingOxidative stress-mediated regulation of proteasome complexesNot4 E3 ligase contributes to proteasome assembly and functional integrity in part through Ecm29Deciphering preferential interactions within supramolecular protein complexes: the proteasome case.Regulation of the 26S proteasome complex during oxidative stressMaturation of the proteasome core particle induces an affinity switch that controls regulatory particle associationLoss of Rpt5 protein interactions with the core particle and Nas2 protein causes the formation of faulty proteasomes that are inhibited by Ecm29 protein.Ethanol and hepatitis C virus suppress peptide-MHC class I presentation in hepatocytes by altering proteasome function.Assembly manual for the proteasome regulatory particle: the first draftThe proteasome: overview of structure and functions.Proteasome allostery as a population shift between interchanging conformersCharacteristics of the turnover of uncoupling protein 3 by the ubiquitin proteasome system in isolated mitochondriaSubcellular distribution and dynamics of active proteasome complexes unraveled by a workflow combining in vivo complex cross-linking and quantitative proteomics.Structure of an endogenous yeast 26S proteasome reveals two major conformational statesKIAA0368-deficiency affects disassembly of 26S proteasome under oxidative stress condition.Phosphorylation of the C-terminal tail of proteasome subunit α7 is required for binding of the proteasome quality control factor Ecm29.
P2860
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P2860
Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh-hant
name
Stability of the proteasome ca ...... its proteolytic active sites.
@en
Stability of the proteasome ca ...... its proteolytic active sites.
@nl
type
label
Stability of the proteasome ca ...... its proteolytic active sites.
@en
Stability of the proteasome ca ...... its proteolytic active sites.
@nl
prefLabel
Stability of the proteasome ca ...... its proteolytic active sites.
@en
Stability of the proteasome ca ...... its proteolytic active sites.
@nl
P2093
P50
P356
P1476
Stability of the proteasome ca ...... f its proteolytic active sites
@en
P2093
Daniel Finley
Maurits F Kleijnen
Nathaniel A Hathaway
Soyeon Park
P2888
P304
P356
10.1038/NSMB1335
P577
2007-11-18T00:00:00Z