Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure.
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Development of new estrogen receptor-targeting therapeutic agents for tamoxifen-resistant breast cancerEstrogen receptor alpha interacts with mitochondrial protein HADHB and affects beta-oxidation activityCeramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemiaExogenous and endogenous ceramides elicit volume-sensitive chloride current in ventricular myocytes.Data mining of NCI's anticancer screening database reveals mitochondrial complex I inhibitors cytotoxic to leukemia cell lines.Tumor suppressor p53 and estrogen receptors in nuclear-mitochondrial communication.Nuclear transcription factors in mammalian mitochondriaProgesterone increases skeletal muscle mitochondrial H2O2 emission in nonmenopausal women.Mitochondria: redox metabolism and dysfunction.Enhancement of apoptotic and autophagic induction by a novel synthetic C-1 analogue of 7-deoxypancratistatin in human breast adenocarcinoma and neuroblastoma cells with tamoxifen.The role of mitochondria in pharmacotoxicology: a reevaluation of an old, newly emerging topic.Regulation of hematopoietic progenitors by estrogens as a basis for new antileukemic strategiesThe essential oils component p-cymene induces proton leak through Fo-ATP synthase and uncoupling of mitochondrial respirationAMPK Activation and Metabolic Reprogramming by Tamoxifen through Estrogen Receptor-Independent Mechanisms Suggests New Uses for This Therapeutic Modality in Cancer TreatmentRegulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications.Selective Disruption of Respiratory Supercomplexes as a New Strategy to Suppress Her2high Breast Cancer.Vitamin C suppresses cell death in MCF-7 human breast cancer cells induced by tamoxifen.Mitochondrial respiratory chain complexes: apoptosis sensors mutated in cancer?Canonical and new generation anticancer drugs also target energy metabolism.A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen.The antiestrogen 4-hydroxytamoxifen protects against isotretinoin-induced permeability transition and bioenergetic dysfunction of liver mitochondria: comparison with tamoxifen.Mitochondria-Targeted Agents: Mitochondriotropics, Mitochondriotoxics, and Mitocans.Cell death-based treatment of neuroblastoma.A transcriptomics model of estrogen action in the ovine fetal hypothalamus: evidence for estrogenic effects of ICI 182,780
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P2860
Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure.
description
2006 nî lūn-bûn
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2006年の論文
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年学术文章
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2006年學術文章
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name
Tamoxifen and estradiol intera ...... ding to mitochondrial failure.
@en
Tamoxifen and estradiol intera ...... ding to mitochondrial failure.
@nl
type
label
Tamoxifen and estradiol intera ...... ding to mitochondrial failure.
@en
Tamoxifen and estradiol intera ...... ding to mitochondrial failure.
@nl
prefLabel
Tamoxifen and estradiol intera ...... ding to mitochondrial failure.
@en
Tamoxifen and estradiol intera ...... ding to mitochondrial failure.
@nl
P2860
P50
P356
P1476
Tamoxifen and estradiol intera ...... ading to mitochondrial failure
@en
P2093
Maria S Santos
P2860
P304
10143-10152
P356
10.1074/JBC.M510249200
P407
P577
2006-01-12T00:00:00Z