Mass measurement and top-down HPLC/MS analysis of intact monoclonal antibodies on a hybrid linear quadrupole ion trap-Orbitrap mass spectrometer.
about
Mass spectrometry-based methods for identifying oxidized proteins in disease: advances and challengesPepsin-Containing Membranes for Controlled Monoclonal Antibody Digestion Prior to Mass Spectrometry Analysis.Top-Down Analysis of Small Plasma Proteins Using an LTQ-Orbitrap. Potential for Mass Spectrometry-Based Clinical Assays for Transthyretin and Hemoglobin.Top-down mass spectrometry for the analysis of combinatorial post-translational modifications.Resolving the micro-heterogeneity and structural integrity of monoclonal antibodies by hybrid mass spectrometric approachesTop Down proteomics: facts and perspectives.Structural and functional characterization of the trifunctional antibody catumaxomabEmerging mass spectrometry-based approaches to probe protein-receptor interactions: focus on overcoming physiological barriersAnalysis of intact protein isoforms by mass spectrometry.Advances and challenges in analytical characterization of biotechnology products: mass spectrometry-based approaches to study properties and behavior of protein therapeuticsMass-spectrometry-based characterization of oxidations in proteins.Ultra high resolution linear ion trap Orbitrap mass spectrometer (Orbitrap Elite) facilitates top down LC MS/MS and versatile peptide fragmentation modes.Analysis of intact monoclonal antibody IgG1 by electron transfer dissociation Orbitrap FTMS.Glycoproteomic analysis of antibodies.Complementary MS methods assist conformational characterization of antibodies with altered S-S bonding networks.100% protein sequence coverage: a modern form of surrealism in proteomics.High-resolution MS for structural characterization of protein therapeutics: advances and future directions.Characterization of immunoglobulin by mass spectrometry with applications for the clinical laboratory.The present state of the art in expression, production and characterization of monoclonal antibodies.Cutting-edge mass spectrometry methods for the multi-level structural characterization of antibody-drug conjugates.Top-Down Mass Spectrometry: Proteomics to Proteoforms.De Novo Sequencing of Top-Down Tandem Mass Spectra: A Next Step towards Retrieving a Complete Protein Sequence.Simple NMR methods for evaluating higher order structures of monoclonal antibody therapeutics with quinary structure.High-throughput middle-down analysis using an orbitrapFourier transform mass spectrometry.Top-down analysis of protein samples by de novo sequencing techniques.What does the future hold for Top Down mass spectrometry?Top-down MS for rapid methionine oxidation site assignment in filgrastim.MS in the analysis of biosimilars.Structural comparison of two anti-CD20 monoclonal antibody drug products using middle-down mass spectrometry.The sweet spot for biologics: recent advances in characterization of biotherapeutic glycoproteins.Combination of SDS-PAGE and intact mass analysis for rapid determination of heterogeneities in monoclonal antibody therapeutics.Analysis of Monoclonal Antibodies in Human Serum as a Model for Clinical Monoclonal Gammopathy by Use of 21 Tesla FT-ICR Top-Down and Middle-Down MS/MS.A Retrospective Evaluation of the Use of Mass Spectrometry in FDA Biologics License Applications.Characterization of a PEGylated protein therapeutic by ion exchange chromatography with on-line detection by native ESI MS and MS/MS.Top-Down Analysis of Branched Proteins Using Mass Spectrometry.Native mass spectrometry combined with enzymatic dissection unravels glycoform heterogeneity of biopharmaceuticals.Exploring an Orbitrap Analyzer for the Characterization of Intact Antibodies by Native Mass Spectrometry
P2860
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P2860
Mass measurement and top-down HPLC/MS analysis of intact monoclonal antibodies on a hybrid linear quadrupole ion trap-Orbitrap mass spectrometer.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh-hant
name
Mass measurement and top-down ...... ap-Orbitrap mass spectrometer.
@en
Mass measurement and top-down ...... ap-Orbitrap mass spectrometer.
@nl
type
label
Mass measurement and top-down ...... ap-Orbitrap mass spectrometer.
@en
Mass measurement and top-down ...... ap-Orbitrap mass spectrometer.
@nl
prefLabel
Mass measurement and top-down ...... ap-Orbitrap mass spectrometer.
@en
Mass measurement and top-down ...... ap-Orbitrap mass spectrometer.
@nl
P2093
P2860
P1476
Mass measurement and top-down ...... ap-Orbitrap mass spectrometer.
@en
P2093
Alexander A Makarov
Pavel V Bondarenko
Tonya P Second
Vlad Zabrouskov
Zhongqi Zhang
P2860
P2888
P304
P356
10.1016/J.JASMS.2009.03.020
P577
2009-03-28T00:00:00Z
P5875
P6179
1001753416