Maternal embryonic leucine zipper kinase transcript abundance correlates with malignancy grade in human astrocytomas. - Wikidata - wikimedia - TriplyDB

Maternal embryonic leucine zipper kinase transcript abundance correlates with malignancy grade in human astrocytomas.

Maternal embryonic leucine zipper kinase transcript abundance correlates with malignancy grade in human astrocytomas.

http://www.wikidata.org/entity/Q46931943

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Maternal embryonic leucine zipper kinase (MELK): a novel regulator in cell cycle control, embryonic development, and cancer Structural Basis for the Regulation of Maternal Embryonic Leucine Zipper Kinase The structures of the kinase domain and UBA domain of MPK38 suggest the activation mechanism for kinase activity Maternal embryonic leucine zipper kinase regulates pancreatic ductal, but not β-cell, regeneration Selection of suitable housekeeping genes for expression analysis in glioblastoma using quantitative RT-PCR Characterization of novel and complex genomic aberrations in glioblastoma using a 32K BAC array.Primary microcephaly: do all roads lead to Rome?Maternal embryonic leucine zipper kinase: key kinase for stem cell phenotype in glioma and other cancers.MELK is an oncogenic kinase essential for mitotic progression in basal-like breast cancer cells.Identification and validation of genes involved in cervical tumourigenesis.The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer.Maternal embryonic leucine zipper kinase enhances gastric cancer progression via the FAK/Paxillin pathway Tumor-specific activation of the C-JUN/MELK pathway regulates glioma stem cell growth in a p53-dependent manner.KIAA0101 is overexpressed, and promotes growth and invasion in adrenal cancer.Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms.Differential expression of ID4 and its association with TP53 mutation, SOX2, SOX4 and OCT-4 expression levels.Gene expression analysis of early stage endometrial cancers reveals unique transcripts associated with grade and histology but not depth of invasion.Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia.NG2 expression in glioblastoma identifies an actively proliferating population with an aggressive molecular signature.The Paf oncogene is essential for hematopoietic stem cell function and development.Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma MELK-a conserved kinase: functions, signaling, cancer, and controversy.Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells Independent and functional validation of a multi-tumour-type proliferation signature.Network-based approach to identify prognostic biomarkers for estrogen receptor-positive breast cancer treatment with tamoxifen MELK-T1, a small-molecule inhibitor of protein kinase MELK, decreases DNA-damage tolerance in proliferating cancer cells Network-based approach identified cell cycle genes as predictor of overall survival in lung adenocarcinoma patients.Stathmin involvement in the maternal embryonic leucine zipper kinase pathway in glioblastoma.Maternal embryonic leucine zipper kinase serves as a poor prognosis marker and therapeutic target in gastric cancer.Maternal embryonic leucine zipper kinase (MELK) reduces replication stress in glioblastoma cells Cell-cycle dependent localization of MELK and its new partner RACK1 in epithelial versus mesenchyme-like cells in Xenopus embryo.3-M syndrome: a growth disorder associated with IGF2 silencing.Identification of IL11RA and MELK amplification in gastric cancer by comprehensive genomic profiling of gastric cancer cell lines.Maternal embryonic leucine zipper kinase is upregulated and required in mammary tumor-initiating cells in vivo.Metabolism and brain cancer.Quantitative proteomic analysis and functional studies reveal that nucleophosmin is involved in cell death in glioblastoma cell line transfected with siRNA.Cortical localization of maternal embryonic leucine zipper kinase (MELK) implicated in cytokinesis in early xenopus embryos.MELK: a potential novel therapeutic target for TNBC and other aggressive malignancies.Expression of stem cell marker and receptor kinase genes in glioblastoma tissue quantified by real-time RT-PCR

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P2860

Maternal embryonic leucine zipper kinase transcript abundance correlates with malignancy grade in human astrocytomas.

http://www.wikidata.org/entity/Q46931943

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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Maternal embryonic leucine zip ...... y grade in human astrocytomas.

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Maternal embryonic leucine zip ...... y grade in human astrocytomas.

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Maternal embryonic leucine zip ...... y grade in human astrocytomas.

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Maternal embryonic leucine zip ...... y grade in human astrocytomas.

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International Journal of Cancer

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Maternal embryonic leucine zip ...... cy grade in human astrocytomas

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Ana Kosoy

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Ana Paula G Hasegawa

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Anamaria A Camargo

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Andrew J Simpson

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Carlos A Moreira-Filho

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Marco A Zago

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Miyuki Uno

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Otavia L Caballero

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Silvia Toledo

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Sueli M Oba-Shinjo

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P2860

Mutation and Functional Analysis of IL-13 Receptors in Human Malignant Glioma Cells

The WHO classification of tumors of the nervous system.

Expression of HOXC9 and E2F2 are up-regulated in CD133(+) cells isolated from human astrocytomas and associate with transformation of human astrocytes.

Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction

M-phase MELK activity is regulated by MPF and MAPK.

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807-815

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scholarly article

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10.1002/IJC.23189

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4

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122

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Oswaldo Keith Okamoto

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2008-02-01T00:00:00Z

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5884501

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17960622

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